• Product name
  • Description
    Rabbit polyclonal to KCNH5
  • Tested applications
    Suitable for: ELISA, WB, IHC-Pmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Mouse, Rat, Rabbit, Horse, Chicken, Guinea pig, Cow, Cat, Dog, Zebrafish
  • Immunogen

    Synthetic peptide derived from a region between amino acids 156-205 of Human KCNH5. Note: The exact sequence is proprietary.

  • Positive control
    • HepG2 cell lysate and human brain tissue.



Our Abpromise guarantee covers the use of ab32975 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
ELISA 1/312500.
WB Use a concentration of 0.5 µg/ml. Detects a band of approximately 60 kDa (predicted molecular weight: 112 kDa). Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.
IHC-P Use at an assay dependent concentration.


  • Relevance
    Voltage-gated potassium (Kv) channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. The KCNH5 gene encodes a member of the potassium channel, voltage-gated, subfamily H. This member is a pore-forming (alpha) subunit of a voltage-gated non-inactivating delayed rectifier potassium channel. KCNH5 is not expressed in differentiating myoblasts.
  • Cellular localization
    Cell Membrane: multi-pass membrane protein.
  • Database links
  • Alternative names
    • EAG2 antibody
    • Ether a go go potassium channel 2 antibody
    • H EAG2 antibody
    • HGNC:6254 antibody
    • Kv10.2 antibody
    • potassium voltage gated channel subfamily H (eag-related) member 5 antibody
    • Voltage gated potassium channel subunit Kv10.2 antibody
    see all

Anti-KCNH5 antibody images

  • Anti-KCNH5 antibody (ab32975) at 0.5 µg/ml + HepG2 cell lysate

    HRP-conjugated anti-rabbit IgG at 1/50000 dilution

    Predicted band size : 112 kDa
    Observed band size : 60 kDa (why is the actual band size different from the predicted?)
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) analysis of human brain tissue labelling KCNH5 at 4-8µg/ml. Neural cells with positive label are indicated by arrows.

References for Anti-KCNH5 antibody (ab32975)

This product has been referenced in:
  • Huang X  et al. Voltage-gated potassium channel EAG2 controls mitotic entry and tumor growth in medulloblastoma via regulating cell volume dynamics. Genes Dev 26:1780-96 (2012). Read more (PubMed: 22855790) »
  • Macaulay EC  et al. Hypomethylation of functional retrotransposon-derived genes in the human placenta. Mamm Genome 22:722-35 (2011). IHC-P ; Human . Read more (PubMed: 21874386) »

See all 2 Publications for this product

Product Wall

Vielen Dank für diese Rückmeldung. Es tut mir wirklich sehr leid, dass Sie keine zufriedenstellenden Ergebnisse erhalten haben! Zu den KCNH5-Antikörpern: Es ist in der Tat sehr einfach, in den 'Additional Notes' eine kurze Notiz zu den erzielten Ergebn...

Read More


Sign up