Overview

  • Product name
    Anti-KCNH8 antibody
  • Description
    Rabbit polyclonal to KCNH8
  • Tested applications
    Suitable for: WBmore details
  • Species reactivity
    Reacts with: Mouse
    Predicted to work with: Rat, Rabbit, Horse, Guinea pig, Cat, Dog, Human, Pig
  • Immunogen

    Synthetic peptide from a region within C terminal amino acids 960-1009: LVGSSPQRTE AHEQNPADSE HHSPNLDYSP HCQVIQEGHL FLRCISP, of Mouse KCNH8 (NP_001026981).

  • Positive control
    • Mouse heart lysate

Properties

  • Form
    Liquid
  • Storage instructions
    Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
  • Storage buffer
    Constituents: 97% PBS, 2% Sucrose
  • Concentration information loading...
  • Purity
    Immunogen affinity purified
  • Clonality
    Polyclonal
  • Isotype
    IgG
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab113944 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 1 µg/ml. Predicted molecular weight: 124 kDa. Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.

Target

  • Function
    Pore-forming (alpha) subunit of voltage-gated potassium channel. Elicits a slowly activating, outward rectifying current. Channel properties may be modulated by cAMP and subunit assembly.
  • Tissue specificity
    Primarily expressed in the nervous system.
  • Sequence similarities
    Belongs to the potassium channel family. H (Eag) (TC 1.A.1.20) subfamily. Kv12.1/KCNH8 sub-subfamily.
    Contains 1 cyclic nucleotide-binding domain.
    Contains 1 PAC (PAS-associated C-terminal) domain.
    Contains 1 PAS (PER-ARNT-SIM) domain.
  • Domain
    The segment S4 is probably the voltage-sensor and is characterized by a series of positively charged amino acids at every third position.
  • Cellular localization
    Membrane.
  • Information by UniProt
  • Database links
  • Alternative names
    • C130090D05Rik antibody
    • ELK antibody
    • ELK channel 3 antibody
    • ELK1 antibody
    • elk3 antibody
    • Ether-a-go-go-like potassium channel 1 antibody
    • Ether-a-go-go-like potassium channel 3 antibody
    • hElk1 antibody
    • Kcnh8 antibody
    • KCNH8_HUMAN antibody
    • Kv12.1 antibody
    • Potassium voltage gated channel, subfamily H (eag-related), member 8 antibody
    • Potassium voltage-gated channel subfamily H member 8 antibody
    • Potassium voltage-gated channel, subfamily H, member 8 antibody
    • Voltage-gated potassium channel subunit Kv12.1 antibody
    see all

Images

  • Anti-KCNH8 antibody (ab113944) at 1 µg/ml + Mouse heart lysate at 10 µg

    Predicted band size : 124 kDa

References

ab113944 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

There are currently no Customer reviews or Questions for ab113944.
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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