Overview

  • Product name
    Anti-KCNK10 antibody
  • Description
    Rabbit polyclonal to KCNK10
  • Tested applications
    Suitable for: WB, ELISAmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Mouse, Rat, Dog
  • Immunogen

    A region within synthetic peptide: HGQGASEDNI INKFGSTSRL TKRKNKDLKK TLPEDVQKIY KTFRNYSLDE, corresponding to C terminal amino acids 434-483 of Human KCNK10

  • Positive control
    • Jurkat cell lysate.

Properties

  • Form
    Liquid
  • Storage instructions
    Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
  • Storage buffer
    Preservative: None
    Constituents: 2% Sucrose, PBS
  • Concentration information loading...
  • Purity
    Protein A purified
  • Clonality
    Polyclonal
  • Isotype
    IgG
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab48868 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 1.4 µg/ml. Detects a band of approximately 56 kDa (predicted molecular weight: 59 kDa). Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.
ELISA 1/312500.

Target

  • Function
    Outward rectifying potassium channel. Produces rapidly activating and non-inactivating outward rectifier K(+) currents. Activated by arachidonic acid and other naturally occurring unsaturated free fatty acids.
  • Tissue specificity
    Abundantly expressed in pancreas and kidney and to a lower level in brain, testis, colon, and small intestine. Isoform b is strongly expressed in kidney (primarily in the proximal tubule) and pancreas, whereas isoform c is abundantly expressed in brain.
  • Sequence similarities
    Belongs to the two pore domain potassium channel (TC 1.A.1.8) family.
  • Cellular localization
    Membrane.
  • Information by UniProt
  • Database links
  • Alternative names
    • 2P domain potassium channel TREK2 antibody
    • K2p10.1 antibody
    • KCNK10 antibody
    • KCNKA_HUMAN antibody
    • Outward rectifying potassium channel protein TREK 2 antibody
    • Outward rectifying potassium channel protein TREK-2 antibody
    • Potassium channel subfamily K member 10 antibody
    • Potassium channel TREK 2 antibody
    • TREK 2 antibody
    • TREK 2 K antibody
    • TREK 2 K(+) channel subunit antibody
    • TREK-2 K(+) channel subunit antibody
    • TREK2 antibody
    • TWIK related K+ channel 2 antibody
    see all

Images

  • Anti-KCNK10 antibody (ab48868) at 1.4 µg/ml (in 5% skimmed milk/PBS) + Jurkat cell lysate at 10 µg

    Secondary
    HRP conjugated anti-Rabbit IgG at 1/50000 dilution

    Predicted band size : 59 kDa
    Observed band size : 56 kDa (why is the actual band size different from the predicted?)

References

ab48868 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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