Anti-TREK1 antibody (ab90855)
Key features and details
- Rabbit polyclonal to TREK1
- Suitable for: WB
- Reacts with: Human
- Isotype: IgG
Overview
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Product name
Anti-TREK1 antibody -
Description
Rabbit polyclonal to TREK1 -
Host species
Rabbit -
Tested applications
Suitable for: WBmore details -
Species reactivity
Reacts with: Human
Predicted to work with: Mouse, Rat, Cow -
Immunogen
Synthetic peptide. This information is proprietary to Abcam and/or its suppliers.
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Positive control
- WB: Human brain membrane lysate.
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General notes
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles. -
Storage buffer
Preservative: 0.05% Sodium azide
Constituent: PBS -
Concentration information loading...
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Purity
Protein A purified -
Clonality
Polyclonal -
Isotype
IgG -
Research areas
Associated products
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Compatible Secondaries
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Isotype control
Applications
The Abpromise guarantee
Our Abpromise guarantee covers the use of ab90855 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Application | Abreviews | Notes |
---|---|---|
WB |
Use a concentration of 2 µg/ml. Predicted molecular weight: 47 kDa.
It is essential to run against membrane preps. |
Notes |
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WB
Use a concentration of 2 µg/ml. Predicted molecular weight: 47 kDa. It is essential to run against membrane preps. |
Target
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Function
Outward rectifying potassium channel. -
Sequence similarities
Belongs to the two pore domain potassium channel (TC 1.A.1.8) family. -
Cellular localization
Membrane. - Information by UniProt
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Database links
- Entrez Gene: 282590 Cow
- Entrez Gene: 3776 Human
- Entrez Gene: 16526 Mouse
- Entrez Gene: 170899 Rat
- Omim: 603219 Human
- SwissProt: O95069 Human
- SwissProt: P97438 Mouse
- Unigene: 497745 Human
see all -
Alternative names
- hTREK 1c antibody
- hTREK 1e antibody
- K2p2.1 antibody
see all
Images
Datasheets and documents
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Datasheet download
References (4)
ab90855 has been referenced in 4 publications.
- Peng Y et al. Activation of TREK1 Channel in the Anterior Cingulate Cortex Improves Neuropathic Pain in a Rat Model. Comput Intell Neurosci 2022:1372823 (2022). PubMed: 36211011
- Li R et al. The transcription factor Foxd3 induces spinal cord ischemia-reperfusion injury by potentiating microRNA-214-dependent inhibition of Kcnk2. Exp Mol Med 52:118-129 (2020). PubMed: 31959866
- Andharia N et al. Involvement of intracellular transport in TREK-1c current run-up in 293T cells. Channels (Austin) 11:224-235 (2017). PubMed: 28085542
- Bieling F et al. Sepsis varies arterial two-pore-domain potassium channel messenger RNA in mice. J Surg Res 193:816-24 (2015). PubMed: 25300694