Overview

  • Product nameAnti-KCNK3 antibody
    See all KCNK3 primary antibodies
  • Description
    Rabbit polyclonal to KCNK3
  • Tested applicationsSuitable for: WB, ELISAmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Mouse, Rat, Sheep, Cow, Dog
  • Immunogen

    A region within synthetic peptide: IPMIIPRDLS TSDTCVEQSH SSPGGGGRYS DTPSRRCLCS GAPRSAISSV, corresponding to C terminal amino acids 325-374 of Human KCNK3

  • Positive control
    • Jurkat cell lysate

Properties

  • FormLiquid
  • Storage instructionsShipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
  • Storage bufferPreservative: None
    Constituents: 2% Sucrose, PBS
  • Concentration information loading...
  • PurityProtein A purified
  • ClonalityPolyclonal
  • IsotypeIgG
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab49433 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 1.25 µg/ml. Detects a band of approximately 38 kDa (predicted molecular weight: 43 kDa). Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.
ELISA Use at an assay dependent concentration.

ELISA: titre using peptide based assay: 1/1562500.

Target

  • FunctionpH-dependent, voltage-insensitive, background potassium channel protein. Rectification direction results from potassium ion concentration on either side of the membrane. Acts as an outward rectifier when external potassium concentration is low. When external potassium concentration is high, current is inward.
  • Tissue specificityWidespread expression in adult. Strongest expression in pancreas and placenta. Lower expression in brain, lung, prostate, heart, kidney, uterus, small intestine and colon.
  • Involvement in diseasePulmonary hypertension, primary, 4
  • Sequence similaritiesBelongs to the two pore domain potassium channel (TC 1.A.1.8) family.
  • Cellular localizationMembrane.
  • Information by UniProt
  • Database links
  • Alternative names
    • Acid sensitive potassium channel protein TASK 1 antibody
    • Acid sensitive potassium channel protein TASK antibody
    • Acid-sensitive potassium channel protein TASK-1 antibody
    • Cardiac two pore background K(+) channel antibody
    • cTBAK 1 antibody
    • K2p3.1 antibody
    • KCNK3 antibody
    • KCNK3_HUMAN antibody
    • OAT1 antibody
    • Potassium channel subfamily K member 3 antibody
    • potassium channel, subfamily K, member 3 antibody
    • Potassium inwardly rectifying channel subfamily K member 3 antibody
    • PPH4 antibody
    • rTASK antibody
    • TASK 1 antibody
    • TASK antibody
    • TBAK1 antibody
    • TWIK related acid sensitive K+ channel antibody
    • TWIK-related acid-sensitive K(+) channel 1 antibody
    • Two P domain potassium channel antibody
    • Two pore K(+) channel KT3. antibody
    • Two pore K(+) channel KT3.1 antibody
    • Two pore potassium channel KT3.1 antibody
    see all

Anti-KCNK3 antibody images

  • Anti-KCNK3 antibody (ab49433) at 1.25 µg/ml + Jurkat cell lysate at 10 µg

    Secondary
    HRP conjugated anti-Rabbit IgG at 1/50000 dilution

    Predicted band size : 43 kDa
    Observed band size : 38 kDa (why is the actual band size different from the predicted?)

References for Anti-KCNK3 antibody (ab49433)

ab49433 has not yet been referenced specifically in any publications.

Product Wall

There are currently no Abreviews or Questions for ab49433.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"