• Product nameAnti-KCNQ4 antibody
    See all KCNQ4 primary antibodies
  • Description
    Goat polyclonal to KCNQ4
  • Specificityab82096 is expected to recognise both reported isoforms (NP_004691.2; NP_751895.1).
  • Tested applicationsSuitable for: WB, ELISAmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Synthetic peptide:


    , corresponding to internal sequence amino acids 601-612 of Human KCNQ4 (NP_004691.2).

  • Positive control
    • Human Brain (Cerebellum) lysates.


  • FormLiquid
  • Storage instructionsShipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid repeated freeze / thaw cycles.
  • Storage bufferPreservative: 0.02% Sodium Azide
    Constituents: 0.5% BSA, Tris saline, pH 7.3
  • Concentration information loading...
  • PurityImmunogen affinity purified
  • Purification notesab82096 was purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
  • ClonalityPolyclonal
  • IsotypeIgG
  • Research areas


Our Abpromise guarantee covers the use of ab82096 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
  • Application notesPeptide ELISA: Antibody detection limit dilution 1/4000.
    WB: Use at a concentration of 1 - 3 µg/ml. Detects a band of approximately 70 kDa (predicted molecular weight: 77 kDa).

    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • Target

    • FunctionProbably important in the regulation of neuronal excitability. May underlie a potassium current involved in regulating the excitability of sensory cells of the cochlea. KCNQ4 channels are blocked by linopirdin, XE991 and bepridil, whereas clofilium is without significant effect. Muscarinic agonist oxotremorine-M strongly suppress KCNQ4 current in CHO cells in which cloned KCNQ4 channels were coexpressed with M1 muscarinnic receptors.
    • Tissue specificityExpressed in the outer, but not the inner, sensory hair cells of the cochlea. Slightly expressed in heart, brain and skeletal muscle.
    • Involvement in diseaseDefects in KCNQ4 are the cause of deafness autosomal dominant type 2A (DFNA2A) [MIM:600101]. DFNA2A is a form of sensorineural hearing loss. Sensorineural deafness results from damage to the neural receptors of the inner ear, the nerve pathways to the brain, or the area of the brain that receives sound information.
    • Sequence similaritiesBelongs to the potassium channel family. KQT (TC 1.A.1.15) subfamily. Kv7.4/KCNQ4 sub-subfamily.
    • DomainThe segment S4 is probably the voltage-sensor and is characterized by a series of positively charged amino acids at every third position.
      The A-domain tail carries the major determinants of channel assembly specificity. Its coiled-coil region is Four-stranded.
    • Cellular localizationBasal cell membrane. Situated at the basal membrane of cochlear outer hair cells.
    • Information by UniProt
    • Database links
    • Alternative names
      • DFNA 2 antibody
      • DFNA2 antibody
      • KCNQ 4 antibody
      • Kcnq4 antibody
      • KCNQ4_HUMAN antibody
      • KQT like 4 antibody
      • KQT-like 4 antibody
      • KV7.4 antibody
      • Potassium channel KQT like 4 antibody
      • Potassium channel subunit alpha KvLQT4 antibody
      • Potassium voltage gated channel KQT like protein 4 antibody
      • Potassium voltage gated channel KQT like subfamily member 4 antibody
      • Potassium voltage gated channel subfamily KQT member 4 antibody
      • Potassium voltage-gated channel subfamily KQT member 4 antibody
      • Voltage gated potassium channel subunit Kv7.4 antibody
      • Voltage-gated potassium channel subunit Kv7.4 antibody
      see all

    Anti-KCNQ4 antibody images

    • Anti-KCNQ4 antibody (ab82096) at 2 µg/ml + Human Cerebellum lysate (in RIPA buffer). at 35 µg
      Developed using the ECL technique

      Predicted band size : 77 kDa
      Observed band size : 70 kDa (why is the actual band size different from the predicted?)

    References for Anti-KCNQ4 antibody (ab82096)

    ab82096 has not yet been referenced specifically in any publications.

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