Overview

  • Product name
    Anti-KCNS1 antibody
  • Description
    Rabbit polyclonal to KCNS1
  • Tested applications
    Suitable for: WBmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Chimpanzee
  • Immunogen

    Synthetic peptide corresponding to a region within N terminal amino acids 2-51 (LMLLVRGTHY ENLRSKVVLP TPLGGRSTET FVSEFPGPDT GIRWRRSDEA) of Human KCNS1 (NP_002242).

  • Positive control
    • HeLa cell lysate.

Properties

Applications

Our Abpromise guarantee covers the use of ab85707 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 1 µg/ml. Predicted molecular weight: 58 kDa. Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.

Target

  • Function
    Potassium channel subunit. Modulates channel activity and reduces the ion flow.
  • Tissue specificity
    Detected in all tissues tested with the exception of skeletal muscle. Highly expressed in adult and fetal brain, fetal kidney and lung, and adult prostate and testis.
  • Sequence similarities
    Belongs to the potassium channel family. S (TC 1.A.1.2) subfamily. Kv9.1/KCNS1 sub-subfamily.
  • Domain
    The segment S4 is probably the voltage-sensor and is characterized by a series of positively charged amino acids at every third position.
  • Cellular localization
    Cell membrane. May not reach the plasma membrane but remain in an intracellular compartment in the absence of KCNB1.
  • Information by UniProt
  • Database links
  • Alternative names
    • Delayed rectifier K(+) channel alpha subunit 1 antibody
    • Delayed-rectifier K(+) channel alpha subunit 1 antibody
    • K+ voltage gated channel, subfamily S, 1 antibody
    • KCNS1 antibody
    • KCNS1_HUMAN antibody
    • KV9.1 antibody
    • OTTHUMP00000031783 antibody
    • potassium voltage gated channel delayed rectifier protein antibody
    • potassium voltage gated channel delayed rectifier protein S1 antibody
    • potassium voltage gated channel, delayed rectifier, subfamily S, member 1 antibody
    • Potassium voltage-gated channel subfamily S member 1 antibody
    • voltage gated potassium channel protein Kv9.1 antibody
    • Voltage gated potassium channel subunit Kv9.1 antibody
    • Voltage-gated potassium channel subunit Kv9.1 antibody
    see all

Images

  • Anti-KCNS1 antibody (ab85707) at 1 µg/ml (5% skim milk / PBS buffer) + HeLa cell lysate at 10 µg

    Secondary
    HRP conjugated anti-Rabbit IgG at 1/50000 dilution

    Predicted band size : 58 kDa
    Observed band size : 58 kDa

References

ab85707 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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