Anti-KCNT1/SLACK antibody (ab167027)
Key features and details
- Rabbit polyclonal to KCNT1/SLACK
- Suitable for: IHC-P
- Reacts with: Human
- Isotype: IgG
Overview
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Product name
Anti-KCNT1/SLACK antibody
See all KCNT1/SLACK primary antibodies -
Description
Rabbit polyclonal to KCNT1/SLACK -
Host species
Rabbit -
Tested applications
Suitable for: IHC-Pmore details -
Species reactivity
Reacts with: Human -
Immunogen
Synthetic peptide corresponding to Human KCNT1/SLACK (C terminal).
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Positive control
- Human Brain, Cortex, Cell Processes.
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General notes
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Store at -20ºC. -
Storage buffer
pH: 7.40
Preservative: 0.02% Sodium azide
Constituents: 49% PBS, 50% Glycerol (glycerin, glycerine), 0.88% Sodium chloride
PBS without Mg2+ and Ca2+. -
Concentration information loading...
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Purity
Immunogen affinity purified -
Clonality
Polyclonal -
Isotype
IgG -
Research areas
Associated products
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Compatible Secondaries
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Isotype control
Applications
The Abpromise guarantee
Our Abpromise guarantee covers the use of ab167027 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Application | Abreviews | Notes |
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IHC-P |
Use a concentration of 5 µg/ml.
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Notes |
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IHC-P
Use a concentration of 5 µg/ml. |
Target
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Function
Outwardly rectifying potassium channel subunit that may co-assemble with other Slo-type channel subunits. Activated by high intracellular sodium or chloride levels. Activated upon stimulation of G-protein coupled receptors, such as CHRM1 and GRIA1. May be regulated by calcium in the absence of sodium ions (in vitro). -
Tissue specificity
Highest expression in liver, brain and spinal cord. Lowest expression in skeletal muscle. -
Sequence similarities
Belongs to the potassium channel family. Calcium-activated (TC 1.A.1.3) subfamily. KCa4.1/KCNT1 sub-subfamily.
Contains 1 RCK N-terminal domain. -
Post-translational
modificationsPhosphorylated by protein kinase C. Phosphorylation of the C-terminal domain increases channel activity. -
Cellular localization
Cell membrane. - Information by UniProt
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Database links
- Entrez Gene: 57582 Human
- Omim: 608167 Human
- SwissProt: Q5JUK3 Human
- Unigene: 104950 Human
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Alternative names
- bA100C15.2 antibody
- EIEE14 antibody
- ENFL5 antibody
see all
Images
Datasheets and documents
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SDS download
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Datasheet download
References (0)
ab167027 has not yet been referenced specifically in any publications.