• Product nameAnti-KCNT1 antibody [S3-26]
    See all KCNT1 primary antibodies
  • Description
    Mouse monoclonal [S3-26] to KCNT1
  • Tested applicationsSuitable for: Flow Cyt, WB, IHC-P, IHC-Fr, ICC, ICC/IFmore details
  • Species reactivity
    Reacts with: Mouse, Rat, Human
  • Immunogen

    Fusion protein: QDEMNDHHQN TLSYVLINPP PDTRLEPNDI VYLIRSDPLA HVTSSSQSRK SSCSNKLSSC NPETRDETQL, corresponding to amino acids 1168-1237 of Rat Kcnt1 (NP_068625)

  • Positive control
    • Rat brain lysate


  • FormLiquid
  • Storage instructionsShipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
  • Storage bufferPreservative: 0.09% Sodium Azide
    Constituents: 50% Glycerol, PBS, pH 7.4
  • Concentration information loading...
  • PurityProtein G purified
  • ClonalityMonoclonal
  • Clone numberS3-26
  • IsotypeIgG1
  • Research areas


Our Abpromise guarantee covers the use of ab94578 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
Flow Cyt Use 1µg for 106 cells. ab170190-Mouse monoclonal IgG1, is suitable for use as an isotype control with this antibody.
WB Use a concentration of 1 - 10 µg/ml. Predicted molecular weight: 137 kDa.
IHC-P Use a concentration of 0.1 - 1 µg/ml.
IHC-Fr Use a concentration of 0.1 - 1 µg/ml.
ICC Use a concentration of 0.1 - 1 µg/ml.
ICC/IF Use a concentration of 1 - 10 µg/ml.


  • FunctionOutwardly rectifying potassium channel subunit that may co-assemble with other Slo-type channel subunits. Activated by high intracellular sodium or chloride levels. Activated upon stimulation of G-protein coupled receptors, such as CHRM1 and GRIA1. May be regulated by calcium in the absence of sodium ions (in vitro).
  • Tissue specificityHighest expression in liver, brain and spinal cord. Lowest expression in skeletal muscle.
  • Sequence similaritiesBelongs to the potassium channel family. Calcium-activated (TC 1.A.1.3) subfamily. KCa4.1/KCNT1 sub-subfamily.
    Contains 1 RCK N-terminal domain.
  • Post-translational
    Phosphorylated by protein kinase C. Phosphorylation of the C-terminal domain increases channel activity.
  • Cellular localizationCell membrane.
  • Information by UniProt
  • Database links
  • Alternative names
    • bA100C15.2 antibody
    • EIEE14 antibody
    • ENFL5 antibody
    • KCa4.1 antibody
    • KCNT1 antibody
    • KCNT1_HUMAN antibody
    • Potassium channel subfamily T member 1 antibody
    • Potassium channel, sodium activated subfamily T, member 1 antibody
    • Potassium channel, subfamily T, member 1 antibody
    • Sequence like a calcium-activated K+ channel antibody
    • SLACK antibody
    • Slo2.2 antibody
    see all

Anti-KCNT1 antibody [S3-26] images

  • Overlay histogram showing SH-SY5Y cells stained with ab94578 (red line). The cells were fixed with 4% paraformaldehyde (10 min) and then permeabilized with 0.1% PBS-Tween for 20 min. The cells were then incubated in 1x PBS / 10% normal goat serum / 0.3M glycine to block non-specific protein-protein interactions followed by the antibody (ab94578, 1µg/1x106 cells) for 30 min at 22ºC. The secondary antibody used was DyLight® 488 goat anti-mouse IgG (H+L) (ab96879) at 1/500 dilution for 30 min at 22ºC. Isotype control antibody (black line) was mouse IgG1 [ICIGG1] (ab91353, 2µg/1x106 cells) used under the same conditions. Acquisition of >5,000 events was performed.

References for Anti-KCNT1 antibody [S3-26] (ab94578)

ab94578 has not yet been referenced specifically in any publications.

Product Wall

There are currently no Abreviews or Questions for ab94578.
Please use the links above to contact us or submit feedback about this product.