Overview

  • Product name
    Anti-KCNT2 antibody [N11/33]
  • Description
    Mouse monoclonal [N11/33] to KCNT2
  • Tested applications
    Suitable for: WB, IHC-P, IHC-Fr, ICC, ICC/IFmore details
  • Species reactivity
    Reacts with: Mouse, Rat
    Predicted to work with: Human
  • Immunogen

    Fusion protein: KNQDQQRKSN VSRSFYHGPS RLPVHSIIAS MGTVAIDLQD TSCRATSGPT LALPSEGGKEL, corresponding to amino acids 564-624 of Mouse KCNT2 (XP_920840)

  • Positive control
    • Rat brain lysate
  • General notes

    The clone number has been updated from S11-33 to N11/33, both clone numbers name the same antibody clone.

     

Properties

  • Form
    Liquid
  • Storage instructions
    Shipped at 4°C. Store at -20°C. Stable for 12 months at -20°C.
  • Storage buffer
    Preservative: 0.09% Sodium Azide
    Constituents: 50% Glycerol, PBS, pH 7.4
  • Concentration information loading...
  • Purity
    Protein G purified
  • Clonality
    Monoclonal
  • Clone number
    N11/33
  • Isotype
    IgG1
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab93602 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB
IHC-P
IHC-Fr
ICC
ICC/IF
  • Application notes
    ICC: Use at a concentration of 0.1 - 1 µg/ml.
    ICC/IF: Use at a concentration of 1 - 10 µg/ml.
    IHC-P: Use at a concentration of 0.1 - 1 µg/ml.
    IHC-Fr: Use at a concentration of 0.1 - 1 µg/ml.
    WB: Use at a concentration of 1.0 - 10 µg/ml. Predicted molecular weight: 131 kDa.


    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • Target

    • Relevance
      KCNT2 belongs to the potassium channel family, calcium-activated subfamily and contains one RCK N-terminal domain. KCNT2 is an outward rectifying potassium channel and produces rapidly activating outward rectifier K(+) currents. It is activated by high intracellular sodium and chloride levels. Channel activity is inhibited by ATP and by inhalation anesthetics, such as isoflurane. KCNT2 is inhibited upon stimulation of G-protein coupled receptors, such as CHRM1 and GRIA1. There are four named isoforms.
    • Cellular localization
      Cell membrane; Multi-pass membrane protein.
    • Database links
    • Alternative names
      • KCa4.2 antibody
      • Potassium channel, subfamily T, member 2 antibody
      • Sequence like an intermediate conductance potassium channel subunit antibody
      • SLICK antibody
      • SLO2.1 antibody
      • Sodium and chloride activated ATP sensitive potassium channel antibody
      • Sodium and chloride activated ATP sensitive potassium channel Slo2.1 antibody
      see all

    Images

    • Immunohistochemical detection of KCNT2 in Mouse backskin sections using ab93602.


    • Predicted band size : 131 kDa
      Western blot detection of KNCT2 in Rat brain membrane lysates using ab93602 at 1:1000 dilution.

    References

    ab93602 has not yet been referenced specifically in any publications.

    Customer reviews and Q&As

    There are currently no Customer reviews or Questions for ab93602.
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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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