Overview

  • Product nameAnti-KCTD12 antibody
    See all KCTD12 primary antibodies
  • Description
    Rabbit polyclonal to KCTD12
  • Tested applicationsSuitable for: WB, IPmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Mouse, Guinea pig, Chimpanzee, Rhesus monkey, Orangutan
  • Immunogen

    Synthetic peptide, corresponding to a region within amino acids 125-175 of Human KCTD12 (NP_612453.1).

  • Positive control
    • 293T, HeLa and Jurkat whole cell lysates

Properties

Applications

Our Abpromise guarantee covers the use of ab124260 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/2000 - 1/10000.
IP Use at 2-10 µg/mg of lysate.

Target

  • FunctionAuxiliary subunit of GABA-B receptors that determine the pharmacology and kinetics of the receptor response. Increases agonist potency and markedly alter the G-protein signaling of the receptors by accelerating onset and promoting desensitization.
  • Tissue specificityPresent in a variety of fetal organs, with highest expression levels in the cochlea and brain and, in stark contrast, is detected only at extremely low levels in adult organs, such as brain and lung.
  • Post-translational
    modifications
    Phosphorylated upon DNA damage, probably by ATM or ATR.
  • Cellular localizationCell junction > synapse > presynaptic cell membrane. Cell junction > synapse > postsynaptic cell membrane.
  • Information by UniProt
  • Database links
  • Alternative names
    • C13orf2 antibody
    • BTB/POZ domain-containing protein KCTD12 antibody
    • KCD12_HUMAN antibody
    • KCTD12 antibody
    • KIAA1778 antibody
    • PFET1 antibody
    • Pfetin antibody
    • potassium channel tetramerisation domain containing 12 USA antibody
    • Predominantly fetal expressed T1 domain antibody
    see all

Anti-KCTD12 antibody images

  • All lanes : Anti-KCTD12 antibody (ab124260) at 0.1 µg/ml

    Lane 1 : 293T whole cell lysate at 50 µg
    Lane 2 : 293T whole cell lysate at 15 µg
    Lane 3 : Jurkat whole cell lysate at 50 µg
    Lane 4 : HeLa whole cell lysate at 50 µg

    Developed using the ECL technique

    Exposure time : 30 seconds
  • Lane 1: ab124260 at 1 µg/ml staining KCTD12 in 293T whole cell lysate immunoprecipitated using ab124260 at 6 µg/mg lysate (1 mg/IP; 20% of IP loaded/lane).
    Lane 2: Control IgG.
    Detection: Chemiluminescence with exposure time of 10 seconds.

References for Anti-KCTD12 antibody (ab124260)

ab124260 has not yet been referenced specifically in any publications.

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