Anti-KDM4B / JMJD2B (phospho T305) antibody (ab103410)

Overview

  • Product name
    Anti-KDM4B / JMJD2B (phospho T305) antibody
    See all KDM4B / JMJD2B primary antibodies
  • Description
    Rabbit polyclonal to KDM4B / JMJD2B (phospho T305)
  • Tested applications
    Suitable for: WBmore details
  • Species reactivity
    Reacts with: Mouse, Human
  • Immunogen

    Synthetic peptide corresponding to Human KDM4B/ JMJD2B aa 281-306 (internal sequence) conjugated to keyhole limpet haemocyanin.
    Database link: O94953

  • Positive control
    • MDA-MB435 and NIH 3T3 cell line lysates

Properties

Applications

Our Abpromise guarantee covers the use of ab103410 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/1000. Predicted molecular weight: 122 kDa.

Target

  • Function
    Histone demethylase that specifically demethylates 'Lys-9' of histone H3, thereby playing a role in histone code. Does not demethylate histone H3 'Lys-4', H3 'Lys-27', H3 'Lys-36' nor H4 'Lys-20'. Only able to demethylate trimethylated H3 'Lys-9', with a weaker activity than KDM4A, KDM4C and KDM4D. Demethylation of Lys residue generates formaldehyde and succinate.
  • Sequence similarities
    Belongs to the JHDM3 histone demethylase family.
    Contains 1 JmjC domain.
    Contains 1 JmjN domain.
    Contains 2 PHD-type zinc fingers.
    Contains 2 Tudor domains.
  • Domain
    The 2 Tudor domains recognize and bind methylated histones. Double Tudor domain has an interdigitated structure and the unusual fold is required for its ability to bind methylated histone tails.
  • Cellular localization
    Nucleus.
  • Information by UniProt
  • Database links
  • Alternative names
    • JHDM3B antibody
    • JmjC domain-containing histone demethylation protein 3B antibody
    • JMJD2B antibody
    • Jumonji domain containing 2B antibody
    • Jumonji domain containing protein 2B antibody
    • Jumonji domain-containing protein 2B antibody
    • Kdm4b antibody
    • KDM4B_HUMAN antibody
    • KIAA0876 antibody
    • Lysine (K) specific demethylase 4B antibody
    • Lysine demethylase 4B antibody
    • Lysine-specific demethylase 4B antibody
    • TDRD14B antibody
    • Tudor domain containing 14B antibody
    see all

Images

  • Anti-KDM4B / JMJD2B (phospho T305) antibody (ab103410) at 1/100 dilution + MDA-MB435 cell line lysates at 35 µg

    Predicted band size : 122 kDa
  • Anti-KDM4B / JMJD2B (phospho T305) antibody (ab103410) at 1/100 dilution + NIH 3T3 cell line lysates at 35 µg

    Predicted band size : 122 kDa

References

ab103410 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

There are currently no Customer reviews or Questions for ab103410.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

Sign up