Overview

  • Product name
    Anti-KDM4D / JMJD2D antibody
    See all KDM4D / JMJD2D primary antibodies
  • Description
    Rabbit polyclonal to KDM4D / JMJD2D
  • Tested applications
    Suitable for: WB, ELISAmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Synthetic peptide from the C-terminal region of human KDM4D/ JMJD2D, conjugated to KLH.

  • Positive control
    • Hela cell line lysate.

Properties

Applications

Our Abpromise guarantee covers the use of ab63199 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/250 - 1/500. Detects a band of approximately 52 kDa (predicted molecular weight: 58 kDa).
ELISA 1/1000.

Target

  • Function
    Histone demethylase that specifically demethylates 'Lys-9' of histone H3, thereby playing a central role in histone code. Does not demethylate histone H3 'Lys-4', H3 'Lys-27', H3 'Lys-36' nor H4 'Lys-20'. Demethylates both di- and trimethylated H3 'Lys-9' residue, while it has no activity on monomethylated residues. Demethylation of Lys residue generates formaldehyde and succinate.
  • Sequence similarities
    Belongs to the JHDM3 histone demethylase family.
    Contains 1 JmjC domain.
    Contains 1 JmjN domain.
  • Cellular localization
    Nucleus.
  • Information by UniProt
  • Database links
  • Alternative names
    • JHD3D antibody
    • JHDM3D antibody
    • JmjC domain-containing histone demethylation protein 3D antibody
    • Jumonji domain-containing protein 2D antibody
    • Kdm4d antibody
    • KDM4D_HUMAN antibody
    • Lysine-specific demethylase 4D antibody
    see all

Images

References

ab63199 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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