Anti-Keratin 8+18+19 antibody [2A4] (ab118855)

Overview

  • Product nameAnti-Keratin 8+18+19 antibody [2A4]
  • Description
    Mouse monoclonal [2A4] to Keratin 8+18+19
  • Tested applicationsSuitable for: WB, IHC-P, IHC-Frmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Cytokeratins purified from pig kidney epithelial cells

  • Positive control
    • Human Breast tissue

Properties

Applications

Our Abpromise guarantee covers the use of ab118855 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/1000 - 1/4000. Predicted molecular weight: 54, 48, 44 kDa.
IHC-P 1/100.
IHC-Fr 1/200.

Target

  • RelevanceKeratin 18 is involved in the uptake of thrombin-antithrombin complexes by hepatic cells By similarity. When phosphorylated, plays a role in filament reorganization. Involved in the delivery of mutated CFTR to the plasma membrane. Together with Keratin 8, is involved in interleukin-6 (IL-6)-mediated barrier protection. Keratin 19 is involved in the organization of myofibers. Together with Keratin 8, helps to link the contractile apparatus to dystrophin at the costameres of striated muscle.
  • Cellular localizationKeratin 8: Cytoplasm. Nucleus: nucleoplasm. Nucleus matrix Keratin 18: Cytoplasm: perinuclear region
  • Database links
  • Alternative names
    • CYK18 antibody
    • Cell proliferation-inducing gene 46 protein antibody
    • CK-18 antibody
    • CK-19 antibody
    • CK-8 antibody
    • CYK8 antibody
    • Cytokeratin-18 antibody
    • Cytokeratin-19 antibody
    • Cytokeratin-8 antibody
    • K19 antibody
    • K8 antibody
    • Keratin, type I cytoskeletal 18 antibody
    • Keratin, type I cytoskeletal 19 antibody
    • Keratin, type II cytoskeletal 8 antibody
    • Keratin-18 antibody
    • Keratin-19 antibody
    • Keratin-8 antibody
    • KRT18 antibody
    • KRT19 antibody
    • KRT8 antibody
    • PIG46 antibody
    • Type-II keratin Kb8 antibody
    see all

Anti-Keratin 8+18+19 antibody [2A4] images

  • Human Breast: Formalin-Fixed, Paraffin-Embedded (FFPE) using ab118855 at a dilution of 1/100.

References for Anti-Keratin 8+18+19 antibody [2A4] (ab118855)

ab118855 has not yet been referenced specifically in any publications.

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