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2A antagonist. Also shows moderate affinity and selectivity for human 5-HT 1Dα over 5-HT 1β, and affinity at α 1 adrenoceptors. Antihypertensive in vivo.
H,3 H)-quinazolinedione tartrate
22H 22FN 3O 3.C 4H 6O 6
Store at Room Temperature. The product can be stored for up to 12 months.
Soluble in DMSO to 100 mM and in water to 10 mM
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
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References for Ketanserin tartrate (ab120132)
This product has been referenced in:
et al. Ketanserin and ritanserin discriminate between recombinant human 5-HT1D alpha and 5-HT1D beta receptor subtypes. Eur J Pharmacol 291:9-15 (1995).
Read more (PubMed: 8549648) »
et al. [3H]ketanserin labels serotonin 5-HT2 and alpha 1-adrenergic receptors in human brain cortex. J Cardiovasc Pharmacol 10 Suppl 3:S48-50 (1987).
Read more (PubMed: 2446070) »
et al. Antihypertensive properties of ketanserin (R 41 468). Fed Proc 42:182-5 (1983).
Read more (PubMed: 6295821) »
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE, NOT FOR USE IN HUMANS"