Anti-ketohexokinase antibody (ab38282)

Overview

• Product name
  Anti-ketohexokinase antibody
  See all ketohexokinase primary antibodies
• Description
  Rabbit polyclonal to ketohexokinase
• Tested applications
  Suitable for: ELISA, WBmore details
• Species reactivity
  Reacts with: Mouse, Human
  
• Immunogen

  Synthetic peptide (Human) selected from the N-terminal region of human KHK conjugated to KLH

• Positive control
  • Mouse liver tissue lysate. 293 cell lysate.

Properties

• Form
  Liquid
• Storage instructions
  Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term.
• Storage buffer
  Preservative: 0.09% Sodium Azide
  Constituents: PBS
• Concentration information loading...
• Purity
  Protein G purified
• Purification notes
  This antibody is purified through a protein G column, eluted out with both high and low pH buffers, neutralized immediately after elution then followed by dialysis against PBS.
• Clonality
  Polyclonal
• Isotype
  IgG
• Research areas
  • Signal Transduction
  • Metabolism
  • Energy Metabolism

  • Cancer
  • Cancer Metabolism
  • Metabolic signaling pathway
  • Metabolism of carbohydrates

  • Metabolism
  • Pathways and Processes
  • Metabolic signaling pathways
  • Carbohydrate metabolism

  • Metabolism
  • Pathways and Processes
  • Metabolic signaling pathways
  • Energy transfer pathways
  • Energy Metabolism

  • Metabolism
  • Types of disease
  • Cancer

Associated products

• Compatible Secondaries
  • Goat Anti-Rabbit IgG H&L (Alexa Fluor® 488) (ab150077)
  • Goat Anti-Rabbit IgG H&L (HRP) (ab205718)
• Positive Controls
  • HEK293 whole cell lysate (ab7902)

Applications

Target

• Tissue specificity
  Most abundant in liver, kidney, gut, spleen and pancreas. Low levels also found in adrenal, muscle, brain and eye.
• Pathway
  Carbohydrate metabolism; fructose metabolism.
• Involvement in disease
  Defects in KHK are the cause of fructosuria (FRUCT) [MIM:229800]. Fructosuria is a benign defect of intermediary metabolism.
• Sequence similarities
  Belongs to the carbohydrate kinase pfkB family.

• Target information above from: UniProt accession P50053 The UniProt Consortium
  The Universal Protein Resource (UniProt) in 2010
  Nucleic Acids Res. 38:D142-D148 (2010) .

  Information by UniProt
• Database links
  • Entrez Gene: 3795 Human
  • Entrez Gene: 16548 Mouse
  • Omim: 614058 Human
  • SwissProt: P50053 Human
  • SwissProt: P97328 Mouse
  • Unigene: 567297 Human
  • Unigene: 22451 Mouse
• Alternative names
  • EC 2.7.1.3 antibody
  • Fructokinase antibody
  • Hepatic fructokinase antibody

  • Ketohexokinase antibody
  • Ketohexokinase isoform a antibody
  • KHK antibody
  • KHK_HUMAN antibody

  see all

Protocols

• Western blot protocols