Anti-ketohexokinase antibody (ab38282)

Overview

• Product nameAnti-ketohexokinase antibodySee all ketohexokinase primary antibodies ...
• Description
  Rabbit polyclonal to ketohexokinase
• Tested applicationsELISA, WB more details
• Species reactivity
  Reacts with: Mouse, Human
  
• Immunogen

  Synthetic peptide (Human) selected from the N-terminal region of human KHK conjugated to KLH

• Positive controlMouse liver tissue lysate. 293 cell lysate.

Properties

• FormLiquid
• Storage instructionsStore at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze / thaw cycles.
• Storage bufferPreservative: 0.09% Sodium Azide
  Constituents: PBS
• Concentration information loading...
• PurityProtein G purified
• Purification notesThis antibody is purified through a protein G column, eluted out with both high and low pH buffers, neutralized immediately after elution then followed by dialysis against PBS.
• Clonality Polyclonal
• IsotypeIgG
• Research Areas
  • Metabolism
  • Types of disease
  • Cancer

  • Metabolism
  • Pathways and Processes
  • Metabolic signaling pathways
  • Carbohydrate metabolism

  • Metabolism
  • Pathways and Processes
  • Metabolic signaling pathways
  • Energy transfer pathways
  • Energy Metabolism

  • Cancer
  • Cancer Metabolism
  • Metabolic signaling pathway
  • Metabolism of carbohydrates

  • Signal Transduction
  • Metabolism
  • Energy Metabolism

Applications

Target

• Tissue specificityMost abundant in liver, kidney, gut, spleen and pancreas. Low levels also found in adrenal, muscle, brain and eye.
• PathwayCarbohydrate metabolism; fructose metabolism.
• Involvement in diseaseDefects in KHK are the cause of fructosuria (FRUCT) [MIM:229800]. Fructosuria is a benign defect of intermediary metabolism.
• Sequence similaritiesBelongs to the carbohydrate kinase pfkB family.

Target information above from: UniProt accession P50053 The UniProt Consortium
The Universal Protein Resource (UniProt) in 2010
Nucleic Acids Res. 38:D142-D148 (2010) .

Information by UniProt
• Database links
  • Entrez Gene: 3795 Human
  • Entrez Gene: 16548 Mouse
  • Omim: 614058 Human
  • SwissProt: Q6IBK2 Human
  • SwissProt: P50053 Human
  • SwissProt: P97328 Mouse
  • Unigene: 567297 Human
  • Unigene: 22451 Mouse

• Alternative names
  EC 2.7.1.3 antibodyfructokinase antibodyHepatic fructokinase antibody

  ketohexokinase antibodyKetohexokinase isoform a antibodyKHK antibodyKHK_HUMAN antibody

  see all

Anti-ketohexokinase antibody images

• 

  Western blot - ketohexokinase antibody (ab38282)
  All lanes : Anti-ketohexokinase antibody (ab38282) at 1/100 dilution
  
  Lane 1 : Mouse liver tissue lysate
  Lane 2 : 293 cell lysate
  
  
  Predicted band size : 33 kDa
  Observed band size : 25 kDa (why is the actual band size different from the predicted?)