Overview

  • Product nameKetotifen fumarate
  • Description
    Selective, H1 antagonist
  • Biological descriptionSelective, non-competitive H1 antagonist. Inhibits phosphodiesterases and blocks Ca2+ channels.
  • Purity> 99%

Properties

  • Chemical name4,9-Dihydro-4-(1-methylpiperidin-4-ylidene)-10H-benzo[4,5]cyclohepta[1,2-b]thiophen-10-one fumarate
  • Molecular weight425.50
  • Chemical structureChemical Structure
  • Molecular formulaC19H19NOS.C4H4O4
  • CAS Number34580-14-8
  • Storage instructionsStore at Room Temperature. The product can be stored for up to 12 months.
  • Solubility overviewSoluble in DMSO to 100 mM
  • Handling

    Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

    Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

  • Source

    Synthetic

  • Research areas

    References for Ketotifen fumarate (ab120782)

    This product has been referenced in:
    • Monument MJ  et al. The mast cell stabilizer ketotifen fumarate lessens contracture severity and myofibroblast hyperplasia: a study of a rabbit model of posttraumatic joint contractures. J Bone Joint Surg Am 92:1468-77 (2010). Read more (PubMed: 20516323) »
    • Sánchez-Patán F  et al. Mast cell inhibition by ketotifen reduces splanchnic inflammatory response in a portal hypertension model in rats. Exp Toxicol Pathol 60:347-55 (2008). Read more (PubMed: 18514499) »
    • Yamada Y  et al. Effect of ketotifen on the production of reactive oxygen species from human eosinophils primed by eotaxin. Pharmacology 69:138-41 (2003). Read more (PubMed: 14512700) »
    • Greenwood C The pharmacology of ketotifen. Chest 82:45S-48S (1982). Read more (PubMed: 6123414) »

    See 0 Publications for this product

    Product Wall

    There are currently no Abreviews or Questions for ab120782.
    Please use the links above to contact us or submit feedback about this product.

    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE, NOT FOR USE IN HUMANS"