Overview

  • Product name
    Anti-KEX2 protease antibody [3B5]
  • Description
    Mouse monoclonal [3B5] to KEX2 protease
  • Tested applications
    Suitable for: Indirect ELISA, WBmore details
  • Species reactivity
    Reacts with: Saccharomyces cerevisiae
  • Immunogen

    Recombinant full length protein (Saccharomyces cerevisiae) -purified Kex2.

  • General notes

    Abcam is committed to meeting high standards of ethical manufacturing and has decided to discontinue this product by June 2019 as it has been generated by the ascites method. We are sorry for any inconvenience this may cause. 

Properties

Applications

Our Abpromise guarantee covers the use of ab34772 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
Indirect ELISA 1/1000 - 1/10000.
WB 1/1000 - 1/5000. Predicted molecular weight: 90 kDa.

Target

  • Relevance
    Kex2 in the yeast Saccharomyces cerevisiae is a transmembrane, Ca2+-dependent serine protease of the subtilisin-like pro-protein convertase (SPC) family with specificity for cleavage after paired basic amino acids. At steady state, Kex2 is predominantly localized in late Golgi compartments and initiates the proteolytic maturation of pro-protein precursors that transit the distal secretory pathway. However, Kex2 localization is not static, and its itinerary apparently involves transiting out of the late Golgi and cycling back from post-Golgi endosomal compartments during its lifetime.
  • Cellular localization
    Golgi apparatus; trans-Golgi network; trans-Golgi network membrane; single-pass type I membrane protein.
  • Database links
    • Alternative names
      • KEX 2 antibody
      • Kex2p antibody
      • Kexin KEX2 antibody
      • QDS1 antibody
      • SRB1 antibody
      • VMA45 antibody
      see all

    Images



    • Predicted band size : 90 kDa

    References

    This product has been referenced in:
    • Liu Y  et al. Non-SCF-type F-box protein Roy1/Ymr258c interacts with a Rab5-like GTPase Ypt52 and inhibits Ypt52 function. Mol Biol Cell 22:1575-84 (2011). WB ; Saccharomyces cerevisiae . Read more (PubMed: 21389113) »

    See 1 Publication for this product

    Customer reviews and Q&As

    Thank you for your email. I apologize for your disappointment. I will try to explain what could have happen. The antibodies ab4644 and ab34772 were dispatched on 4th july and were delivered on 7th July. I am not sure if the person who received t...

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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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