KG-1 nuclear extract lysate (ab14854)

Overview

  • Product name
    KG-1 nuclear extract lysate
  • General notes
    Extracts have been quality control tested by Western blot and the Electrophoretic Mobility Shift Assay (EMSA).

Properties

  • Form
    Liquid
  • Storage instructions
    Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.
  • Storage buffer
    Preservative: None
    Constituents: 20% Glycerol, 20mM HEPES, 100mM Potassium Chloride, 1mM Magnesium Chloride, 0.5mM PMSF, 0.5mM DTT. pH 7.9
  • Concentration information loading...
  • Research areas
  • Background
    Myeloid dendritic cells (DC) are representatives of a rare and phenotypically diverse population of professional antigen presenting cells possessing high functional heterogeneity and flexibility. KG-1 cells are used as an erythroleukemia model cell line, which shares morphological and physiological similarities with immature and mature myeloid DC. These cells posses numerous tumor markers and other antigens (DR, Ia-like antigens) and are used in studies of tumorigenicity, differentiation. They are CD3 negative, CD4 negative, CD13 positive , CD14 negative, CD15 positive, CD19 negative, CD33 positive, CD34 positive, HLA-DR positive.

References

ab14854 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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