Overview

  • Product name
  • Description
    Rabbit polyclonal to KHDRBS2
  • Host species
    Rabbit
  • Tested applications
    Suitable for: WBmore details
  • Species reactivity
    Reacts with: Rat, Human
  • Immunogen

    Synthetic peptide within Human KHDRBS2 aa 298-321 (C terminal) conjugated to Keyhole Limpet Haemocyanin (KLH). The exact sequence is proprietary.
    Database link: Q5VWX1

  • Positive control
    • HeLa and rat testis lysates.

Properties

Applications

Our Abpromise guarantee covers the use of ab188382 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/1000. Predicted molecular weight: 39 kDa.

Target

  • Function
    RNA-binding protein that plays a role in the regulation of alternative splicing and influences mRNA splice site selection and exon inclusion. Its phosphorylation by FYN inhibits its ability to regulate splice site selection. Induces an increased concentration-dependent incorporation of exon in CD44 pre-mRNA by direct binding to purine-rich exonic enhancer. May function as an adapter protein for Src kinases during mitosis. Binds both poly(A) and poly(U) homopolymers. Phosphorylation by PTK6 inhibits its RNA-binding ability.
  • Tissue specificity
    Highly expressed in brain, lung, kidney and small intestine. Weakly expressed in placenta, liver, spleen, thymus, ovary and colon.
  • Sequence similarities
    Belongs to the KHDRBS family.
    Contains 1 KH domain.
  • Post-translational
    modifications
    Methylated.
    Tyrosine phosphorylated by FYN, PTK6 and SRC. Tyrosine phosphorylated by SRC during mitosis.
  • Cellular localization
    Nucleus.
  • Information by UniProt
  • Database links
  • Alternative names
    • KH domain containing, RNA binding, signal transduction associated protein 2 antibody
    • 6330586C16Rik antibody
    • bA535F17.1 antibody
    • FLJ38664 antibody
    • hSLM 1 antibody
    • hSLM-1 antibody
    • KH domain containing, RNA binding, signal transduction associated 2 antibody
    • KH domain-containing antibody
    • KHDR2_HUMAN antibody
    • khdrbs2 antibody
    • MGC26664 antibody
    • RNA-binding antibody
    • Sam68 like mammalian protein 1 antibody
    • Sam68-like mammalian protein 1 antibody
    • signal transduction-associated protein 2 antibody
    • SLM 1 antibody
    • SLM-1 antibody
    • SLM1 antibody
    see all

Images

  • All lanes : Anti-KHDRBS2 antibody (ab188382) at 1/1000 dilution

    Lane 1 : HeLa cell lysate
    Lane 2 : Rat testis lysate

    Lysates/proteins at 35 µg per lane.

    Predicted band size: 39 kDa

References

ab188382 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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