Overview

  • Product nameAnti-KHDRBS2 antibody
    See all KHDRBS2 primary antibodies
  • Description
    Rabbit polyclonal to KHDRBS2
  • Tested applicationsSuitable for: WBmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Mouse, Rat, Rabbit, Horse, Chicken, Guinea pig, Cow, Cat, Dog, Zebrafish
  • Immunogen

    Synthetic peptide corresponding to a region within internal sequence amino acids 144-193 (AYSRMSHALE EIKKFLVPDY NDEIRQEQLR ELSYLNGSED SGRGRGIRGR) of Human KHDRBS2 (NP_689901).

  • Positive control
    • Fetal liver lysate

Properties

Applications

Our Abpromise guarantee covers the use of ab94453 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 1 µg/ml. Predicted molecular weight: 39 kDa. Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.

Target

  • FunctionRNA-binding protein that plays a role in the regulation of alternative splicing and influences mRNA splice site selection and exon inclusion. Its phosphorylation by FYN inhibits its ability to regulate splice site selection. Induces an increased concentration-dependent incorporation of exon in CD44 pre-mRNA by direct binding to purine-rich exonic enhancer. May function as an adapter protein for Src kinases during mitosis. Binds both poly(A) and poly(U) homopolymers. Phosphorylation by PTK6 inhibits its RNA-binding ability.
  • Tissue specificityHighly expressed in brain, lung, kidney and small intestine. Weakly expressed in placenta, liver, spleen, thymus, ovary and colon.
  • Sequence similaritiesBelongs to the KHDRBS family.
    Contains 1 KH domain.
  • Post-translational
    modifications
    Methylated.
    Tyrosine phosphorylated by FYN, PTK6 and SRC. Tyrosine phosphorylated by SRC during mitosis.
  • Cellular localizationNucleus.
  • Information by UniProt
  • Database links
  • Alternative names
    • KH domain containing, RNA binding, signal transduction associated protein 2 antibody
    • 6330586C16Rik antibody
    • bA535F17.1 antibody
    • FLJ38664 antibody
    • hSLM 1 antibody
    • hSLM-1 antibody
    • KH domain containing, RNA binding, signal transduction associated 2 antibody
    • KH domain-containing antibody
    • KHDR2_HUMAN antibody
    • khdrbs2 antibody
    • MGC26664 antibody
    • RNA-binding antibody
    • Sam68 like mammalian protein 1 antibody
    • Sam68-like mammalian protein 1 antibody
    • signal transduction-associated protein 2 antibody
    • SLM 1 antibody
    • SLM-1 antibody
    • SLM1 antibody
    see all

Anti-KHDRBS2 antibody images

  • Anti-KHDRBS2 antibody (ab94453) at 1 µg/ml (in 5% skim milk / PBS buffer) + Human fetal liver lysate at 10 µg

    Secondary
    HRP conjugated anti-Rabbit IgG at 1/50000 dilution

    Predicted band size : 39 kDa

References for Anti-KHDRBS2 antibody (ab94453)

ab94453 has not yet been referenced specifically in any publications.

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