Fast track antibodies constitute a diverse group of products that have been released to accelerate your research, but are not yet fully characterized. They have all been affinity purified and show high titre values against the immunizing peptide (by ELISA).
Use at an assay dependent concentration. Predicted molecular weight: 12 kDa. Preliminary experiments gave an approx 30kDa band in Human Colon, Kidney, Thymus and Tonsil lysates after 0.01µg/ml antibody staining. Please note that currently we cannot find an explanation in the literature for the band we observe given the calculated size of 12.0kDa according to NP_055551.1. The 30kDa band was successfully blocked by incubation with the immunizing peptide.
May be involved in protection of cells from UV-induced cell death.
Expressed predominantly in liver, pancreas and placenta. Not detected in heart or brain. Highly expressed in a number of tumors, especially esophageal tumors, in anaplastic thyroid carcinomas and in non-small-cell lung cancer lines.
Liu L et al. Variant 2 of KIAA0101, antagonizing its oncogenic variant 1, might be a potential therapeutic strategy in hepatocellular carcinoma. Oncotarget8:43990-44003 (2017).
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