• Product nameAnti-KIAA0319 antibody
    See all KIAA0319 primary antibodies
  • Description
    Goat polyclonal to KIAA0319
  • SpecificityThis antibody is expected to cross-react with mouse KIAA0319 isoform 1 (NP_001074520.1), isoform 2 (XP_994023.1) and isoform 4 (XP_913491.1).
  • Tested applicationsSuitable for: WBmore details
  • Species reactivity
    Reacts with: Mouse
    Predicted to work with: Rat
  • Immunogen

    Synthetic peptide:


    , corresponding to internal sequence amino acids 391-403 of Mouse KIAA0319 (NP_001074520.1).

  • Positive control
    • Mouse Brain lysate
  • General notes

    The variants XP_341528.2 and XP_001070349.1 represent identical protein.


  • FormLiquid
  • Storage instructionsShipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid repeated freeze / thaw cycles.
  • Storage bufferPreservative: 0.02% Sodium Azide
    Constituents: 0.5% BSA, Tris saline, pH 7.3
  • Concentration information loading...
  • PurityImmunogen affinity purified
  • Purification notesab82212 is purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
  • Primary antibody notesThe variants XP_341528.2 and XP_001070349.1 represent identical protein.
  • ClonalityPolyclonal
  • IsotypeIgG
  • Research areas


Our Abpromise guarantee covers the use of ab82212 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 0.5 - 1.5 µg/ml. Predicted molecular weight: 118 kDa.


  • FunctionInvolved in neuronal migration during development of the cerebral neocortex. May function in a cell autonomous and a non-cell autonomous manner and play a role in appropriate adhesion between migrating neurons and radial glial fibers. May also regulate growth and differentiation of dendrites.
  • Tissue specificityDetected in adult brain cortex and fetal frontal lobe (at protein level). Highly expressed in brain cortex, putamen, amygdala, hippocampus and cerebellum.
  • Involvement in diseaseDefects in KIAA0319 may be a cause of susceptibility to dyslexia type 2 (DYX2) [MIM:600202]; also known as specific reading disability type 2. Dyslexia is a relatively common, complex cognitive disorder that affects 5% to 10% of school-aged children. The disorder is characterized by an impairment of reading performance despite adequate motivational, educational and intellectual opportunities and in the absence of sensory or neurological disability. Note=A lower expression is associated with the risk haplotype.
  • Sequence similaritiesContains 1 MANSC domain.
    Contains 5 PKD domains.
  • Developmental stageExpressed in the developing cerebral neocortex and glanglionic eminence in 57 days post-fertilization fetal brain.
  • Post-translational
    Shedding of the extracellular domain and intramembrane cleavage produce several proteolytic products. The intramembrane cleavage releases a soluble cytoplasmic polypeptide that translocates to the nucleolus.
  • Cellular localizationCell membrane. Early endosome membrane. Low-abundance isoforms lacking the transmembrane domain have been described; these are secreted.
  • Information by UniProt
  • Database links
  • Alternative names
    • DLX 2 antibody
    • DLX2 antibody
    • DYLX 2 antibody
    • DYLX2 antibody
    • Dyslexia susceptibility 2 antibody
    • Dyslexia-associated protein KIAA0319 antibody
    • DYX 2 antibody
    • DYX2 antibody
    • K0319_HUMAN antibody
    • Kiaa0319 antibody
    • MGC176717 antibody
    see all

Anti-KIAA0319 antibody images

  • Anti-KIAA0319 antibody (ab82212) at 0.5 µg/ml + Mouse Brain lysate (in RIPA buffer) at 35 µg
    Developed using the ECL technique

    Predicted band size : 118 kDa
    Observed band size : 150 kDa (why is the actual band size different from the predicted?)
    Additional bands at : 25 kDa. We are unsure as to the identity of these extra bands.

References for Anti-KIAA0319 antibody (ab82212)

ab82212 has not yet been referenced specifically in any publications.

Product Wall

There are currently no Abreviews or Questions for ab82212.
Please use the links above to contact us or submit feedback about this product.