Overview

  • Product name
  • Description
    Rabbit polyclonal to KIAA0652
  • Tested applications
    Suitable for: WB, IHC-Pmore details
  • Species reactivity
    Reacts with: Mouse, Human
    Predicted to work with: Cow, Zebrafish
  • Immunogen

    Recombinant fragment corresponding to a region within amino acids 1-178 of Human KIAA0652 (UniProt ID: O75143).

  • Positive control
    • NT2D1, PC3 and Mouse brain whole cell lysates. Human gastric carcinoma tissue.
  • General notes
    Store as concentrated solution.

Properties

Applications

Our Abpromise guarantee covers the use of ab155826 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/500 - 1/3000. Predicted molecular weight: 56 kDa.
IHC-P 1/100 - 1/1000.

Target

  • Function
    Autophagy factor required for autophagosome formation. Target of the TOR kinase signaling pathway that regulates autophagy through the control of the phosphorylation status of ATG13 and ULK1, and the regulation of the ATG13-ULK1-RB1CC1 complex.
  • Sequence similarities
    Belongs to the ATG13 metazoan family.
  • Post-translational
    modifications
    Phosphorylated by ULK1 and ULK2. Phosphorylation status depends on nutrient-rich conditions; dephosphorylated during starvation or following treatment with rapamycin.
  • Cellular localization
    Cytoplasm > cytosol. Preautophagosomal structure. Under starvation conditions, is localized to puncate structures primarily representing the isolation membrane and the isolation membrane sequesters a portion of the cytoplasm resulting in autophagosome formation.
  • Information by UniProt
  • Database links
  • Alternative names
    • ATG13 antibody
    • ATG13 autophagy related 13 homolog (S. cerevisiae) antibody
    • ATG13_HUMAN antibody
    • Autophagy related 13 antibody
    • Autophagy related protein 13 antibody
    • Autophagy-related protein 13 antibody
    • FLJ20698 antibody
    • KIAA0652 antibody
    • OTTHUMP00000233321 antibody
    • OTTHUMP00000233322 antibody
    • OTTHUMP00000233323 antibody
    • OTTHUMP00000233324 antibody
    • OTTHUMP00000233325 antibody
    • OTTHUMP00000233326 antibody
    see all

Images

  • Anti-KIAA0652 antibody (ab155826) at 1/1000 dilution + Mouse brain whole cell lysates at 50 µg

    Predicted band size : 56 kDa
  • All lanes : Anti-KIAA0652 antibody (ab155826) at 1/2000 dilution

    Lane 1 : NT2D1 cell lysates
    Lane 2 : PC3 cell lysates

    Lysates/proteins at 30 µg per lane.


    Predicted band size : 56 kDa
  • Immunohistochemical analysis of paraffin embedded Human gastric carcinoma tissue, labeling KIAA0652 using ab155826 at 1/500 dilution.

References

ab155826 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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