Overview

  • Product nameAnti-KIAA1279 antibody
    See all KIAA1279 primary antibodies
  • Description
    Rabbit polyclonal to KIAA1279
  • Tested applicationsSuitable for: WBmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Mouse, Rat, Rabbit, Horse, Guinea pig, Cow, Cat, Dog
  • Immunogen

    Synthetic peptide corresponding to a region within C terminal amino acids 336-385 (LDLDKQSELR ALRKKELDEE ESIRKKAVQF GTGELCDAIS AVEEKVSYLR) of Human KIAA1279 (NP_056449).

  • Positive control
    • HT1080 cell lysate

Properties

Applications

Our Abpromise guarantee covers the use of ab122985 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 1 µg/ml. Predicted molecular weight: 72 kDa. Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.

Target

  • FunctionRequired for organization of axonal microtubules, and axonal outgrowth and maintenance during peripheral and central nervous system development. Regulates mitochondrial transport by modulating KIF1B motor activity.
  • Tissue specificityHighly expressed in heart, brain, ovary, testis, spinal cord and all specific brain regions examined. Moderate expressed at intermediate level in all other adult tissues examined, as well as in fetal liver and brain. Not expressed in blood leukocytes.
  • Involvement in diseaseDefects in KIAA1279 are the cause of Goldberg-Shprintzen megacolon syndrome (GOSHS) [MIM:609460]. GOSHS is characterized by microcephaly, mental retardation and facial dysmorphism, as well as phenotypes related to Hirschsprung disease syndrome.
  • Sequence similaritiesBelongs to the KIF1-binding protein family.
  • Cellular localizationMitochondrion.
  • Information by UniProt
  • Database links
  • Alternative names
    • Hypothetical protein LOC26128 antibody
    • KBP antibody
    • KBP_HUMAN antibody
    • KIAA1279 antibody
    • KIF1-binding protein antibody
    • TTC20 antibody
    • Uncharacterized protein KIAA1279 antibody
    see all

Anti-KIAA1279 antibody images

  • Anti-KIAA1279 antibody (ab122985) at 1 µg/ml + HT10180 cell lysate at 10 µg

    Predicted band size : 72 kDa

References for Anti-KIAA1279 antibody (ab122985)

ab122985 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"