Overview

  • Product nameAnti-KIAA1279 antibody
    See all KIAA1279 primary antibodies
  • Description
    Mouse polyclonal to KIAA1279
  • Tested applicationsSuitable for: WBmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Full length human protein (NP_056449, aa 1-621)

  • Positive control
    • KIAA1279-transfected 293T cell lysate

Properties

Applications

Our Abpromise guarantee covers the use of ab68955 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/500 - 1/1000. Predicted molecular weight: 72 kDa.

Target

  • FunctionRequired for organization of axonal microtubules, and axonal outgrowth and maintenance during peripheral and central nervous system development. Regulates mitochondrial transport by modulating KIF1B motor activity.
  • Tissue specificityHighly expressed in heart, brain, ovary, testis, spinal cord and all specific brain regions examined. Moderate expressed at intermediate level in all other adult tissues examined, as well as in fetal liver and brain. Not expressed in blood leukocytes.
  • Involvement in diseaseDefects in KIAA1279 are the cause of Goldberg-Shprintzen megacolon syndrome (GOSHS) [MIM:609460]. GOSHS is characterized by microcephaly, mental retardation and facial dysmorphism, as well as phenotypes related to Hirschsprung disease syndrome.
  • Sequence similaritiesBelongs to the KIF1-binding protein family.
  • Cellular localizationMitochondrion.
  • Information by UniProt
  • Database links
  • Alternative names
    • Hypothetical protein LOC26128 antibody
    • KBP antibody
    • KBP_HUMAN antibody
    • KIAA1279 antibody
    • KIF1-binding protein antibody
    • TTC20 antibody
    • Uncharacterized protein KIAA1279 antibody
    see all

Anti-KIAA1279 antibody images

  • All lanes : Anti-KIAA1279 antibody (ab68955) at 1/500 dilution

    Lane 1 : KIAA1279 transfected 293T cell lysate
    Lane 2 : Non-transfected 293T cell lysate

    Lysates/proteins at 25 µg per lane.

    Secondary
    Goat Anti-Mouse IgG (H&L)-HRP conjugated at 1/2500 dilution

    Predicted band size : 72 kDa
    Observed band size : 55 kDa (why is the actual band size different from the predicted?)

References for Anti-KIAA1279 antibody (ab68955)

ab68955 has not yet been referenced specifically in any publications.

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