Overview

  • Product name
  • Description
    Rabbit polyclonal to KIAA1543
  • Tested applications
    Suitable for: IHC-Pmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    antigen sequence: LRHQPILMGA HLAVIDALMA AFAFEWTKTL PGPLALTSLE HKLLFWVDTT VRRLQEKTEQ EAAQRASPAA PADGAAPAQP SIRYRKDR, corresponding to amino acids 127-214 of Human KIAA1543 isoform 1 (Q9P1Y5).

  • Positive control
    • Human colon tissue.

Properties

  • Form
    Liquid
  • Storage instructions
    Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
  • Storage buffer
    pH: 7.20
    Preservative: 0.02% Sodium azide
    Constituents: 59% PBS, 40% Glycerol
  • Concentration information loading...
  • Purity
    Immunogen affinity purified
  • Clonality
    Polyclonal
  • Isotype
    IgG
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab122864 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-P 1/50 - 1/200. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.

Target

  • Function
    Microtubule minus-end binding protein that acts as a regulator of microtubule dynamics. Specifically required for zonula adherens biogenesis and maintenance by anchoring microtubules at their minus-ends to zonula adherens, leading to recruit KIFC3 kinesin to junctional site.
  • Sequence similarities
    Belongs to the CAMSAP1 family.
    Contains 1 CH (calponin-homology) domain.
    Contains 1 CKK domain.
  • Domain
    The CKK domain binds microtubules.
  • Cellular localization
    Cell junction > adherens junction. Cytoplasm. Cytoplasm > cytoskeleton. Scattered in the cytoplasm. Localizes along zonula adherens only at mature cell-cell contacts.
  • Information by UniProt
  • Database links
  • Alternative names
    • Calmodulin regulated spectrin associated protein family, member 3 antibody
    • Calmodulin-regulated spectrin-associated protein 3 antibody
    • CAMP3_HUMAN antibody
    • KIAA1543 antibody
    • NEZHA antibody
    • Protein Nezha antibody
    see all

Images

  • ab122864 at 1/50 dilution staining KIAA1543 in paraffin-embedded Human colon tissue by Immunohistochemistry.

References

ab122864 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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