Overview

  • Product name
  • Description
    Rabbit polyclonal to KIF13A
  • Specificity
    Cross reacts with many mammalian proteins due to sequence homology.
  • Tested applications
    Suitable for: IHC-P, WBmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Synthetic peptide within Human KIF13A (internal sequence). The exact sequence is proprietary.
    Database link: KIF13A

Properties

  • Form
    Liquid
  • Storage instructions
    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle.
  • Storage buffer
    Constituents: 1.21% Tris, 0.75% Glycine, 2% Sucrose
  • Concentration information loading...
  • Purity
    Protein A purified
  • Clonality
    Polyclonal
  • Isotype
    IgG
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab181879 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-P 1/200 - 1/2000.
WB 1/500 - 1/5000. Predicted molecular weight: 202 kDa.

Target

  • Function
    Plus end-directed microtubule-dependent motor protein involved in intracellular transport and regulating various processes such as mannose-6-phosphate receptor (M6PR) transport to the plasma membrane, endosomal sorting during melanosome biogenesis and cytokinesis. Mediates the transport of M6PR-containing vesicles from trans-Golgi network to the plasma membrane via direct interaction with the AP-1 complex. During melanosome maturation, required for delivering melanogenic enzymes from recycling endosomes to nascent melanosomes by creating peripheral recycling endosomal subdomains in melanocytes. Also required for the abcission step in cytokinesis: mediates translocation of ZFYVE26, and possibly TTC19, to the midbody during cytokinesis.
  • Tissue specificity
    Widely expressed, with highest levels in heart, brain and skeletal muscle.
  • Sequence similarities
    Belongs to the kinesin-like protein family.
    Contains 1 FHA domain.
    Contains 1 kinesin-motor domain.
  • Developmental stage
    Expressed at very low level in most fetal tissues, but at higher levels in skeletal muscle and lung.
  • Cellular localization
    Cytoplasm > cytoskeleton > centrosome. Midbody. Endosome membrane. Golgi apparatus membrane. Recruited to the midbody during cytokinesis.
  • Information by UniProt
  • Database links
  • Alternative names
    • bA500C11.2 antibody
    • FLJ27232 antibody
    • Homolog of mouse KIF13A mannose 6 phosphate receptor transporter antibody
    • KI13A_HUMAN antibody
    • KIF 13A antibody
    • Kif13a antibody
    • Kinesin family member 13A antibody
    • Kinesin like protein KIF13A antibody
    • Kinesin like protein RBKIN antibody
    • Kinesin-like protein KIF13A antibody
    • Kinesin-like protein RBKIN antibody
    • RBKIN antibody
    see all

References

ab181879 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

There are currently no Customer reviews or Questions for ab181879.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

Sign up