Overview

  • Product nameAnti-KIF14 antibody
    See all KIF14 primary antibodies
  • Description
    Rabbit polyclonal to KIF14
  • Tested applicationsSuitable for: IHC-P, ICCmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Chimpanzee, Gorilla
  • Immunogen

    Synthetic peptide, corresponding to a region between amino acids 1600 and the C terminus (amino acid 1648) of Human KIF14 (NP_055690.1).

  • Positive control
    • Formaldehyde fixed asynchronous HeLa cells.

Properties

Applications

Our Abpromise guarantee covers the use of ab92429 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-P
ICC
  • Application notesICC/IF: Use at an assay dependent dilution.
    IHC-P (formaldehyde fixed): 1/100 - 1/500.

    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • Target

    • FunctionPlays an essential role in cytokinesis.
    • Sequence similaritiesBelongs to the kinesin-like protein family.
      Contains 1 FHA domain.
      Contains 1 kinesin-motor domain.
    • Developmental stageUp-regulated in cells progressing through G2/M phase.
    • Cellular localizationNucleus. Cytoplasm. Cytoplasm > cytoskeleton > spindle. Nuclear localization observed during interphase in PubMed:16431929 or triggered by entry into mitosis in PubMed:16648480. Cytoplasmic in interphase (PubMed:16648480) and metaphase cells (PubMed:16431929). From prophase to metaphase, accumulates at the developing spindle poles and their associated microtubules. During anaphase, accumulates at the spindle midzone. Localization to the central spindle and midbody during anaphase is dependent upon PRC1 and CIT presence. In cells ready to undergo abscission, concentrates at the contractile ring.
    • Information by UniProt
    • Database links
    • Alternative names
      • KIAA0042 antibody
      • KIF 14 antibody
      • KIF14 antibody
      • KIF14_HUMAN antibody
      • Kinesin Family Member 14 antibody
      • Kinesin like protein KIF14 antibody
      • Kinesin-like protein KIF14 antibody
      • MGC142302 antibody
      see all

    Anti-KIF14 antibody images

    • Formaldehyde fixed asynchronous HeLa cells detected with ab92429 at a 1/100 dilution.
      Detection: Red-fluorescent goat anti-rabbit IgG highly cross-adsorbed, used at a dilution of 1/100.

    References for Anti-KIF14 antibody (ab92429)

    ab92429 has not yet been referenced specifically in any publications.

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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"