Overview

  • Product name
  • Description
    Rabbit polyclonal to KIF18A
  • Tested applications
    Suitable for: IPmore details
    Unsuitable for: WB
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Synthetic peptide corresponding to a region between residues 650 and 700 of human KIF18A (NP_112494.2)

  • Positive control
    • HeLa whole cell lysate.

Properties

  • Form
    Liquid
  • Storage instructions
    Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
  • Storage buffer
    Preservative: 0.09% Sodium Azide
    Constituents: 8mM PBS, 60mM Citrate, 150mM Tris, pH 7-8
  • Concentration information loading...
  • Purity
    Immunogen affinity purified
  • Purification notes
    ab72416 was affinity purified using an epitope specific to KIF18A immobilized on solid support.
  • Clonality
    Polyclonal
  • Isotype
    IgG
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab72416 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IP Use at 2-5 µg/mg of lysate.
  • Application notes
    Is unsuitable for WB.
  • Target

    • Function
      Microtubule-depolymerizing kinesin which plays a role in chromosome congression by reducing the amplitude of preanaphase oscillations and slowing poleward movement during anaphase, thus suppressing chromosome movements. May stabilize the CENPE-BUB1B complex at the kinetochores during early mitosis and maintains CENPE levels at kinetochores during chromosome congression.
    • Sequence similarities
      Belongs to the kinesin-like protein family.
      Contains 1 kinesin-motor domain.
    • Post-translational
      modifications
      Glycosylated.
      Ubiquitinated.
    • Cellular localization
      Cell projection > ruffle. Cytoplasm. Nucleus. Cytoplasm > cytoskeleton > centrosome.
    • Information by UniProt
    • Database links
    • Alternative names
      • AU024633 antibody
      • B130001M12Rik antibody
      • DKFZp434G2226 antibody
      • KI18A_HUMAN antibody
      • KIF 18A antibody
      • KIF18A antibody
      • kinesin family member 18A antibody
      • Kinesin like protein KIF18A antibody
      • Kinesin-like protein KIF18A antibody
      • Marrow stromal KIF18A antibody
      • MGC27627 antibody
      • MS KIF18A antibody
      • MS-KIF18A antibody
      • RGD1561740 antibody
      • RP23 206C1.1 antibody
      see all

    Images

    • Detection of KIF18A by Western Blot of Immunprecipitate.
      anti-KIF18A at 1µg/ml staining KIF18A in HeLa whole cell lysate immunoprecipitated using ab72416 at 3µg/mg lysate (1 mg/IP; 20% of IP loaded/lane).
      Detection: Chemiluminescence with exposure time of 30 seconds.

    References

    This product has been referenced in:
    • Chen QI  et al. Elevated expression of KIF18A enhances cell proliferation and predicts poor survival in human clear cell renal carcinoma. Exp Ther Med 12:377-383 (2016). WB . Read more (PubMed: 27347065) »

    See 1 Publication for this product

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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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