Overview

  • Product nameAnti-Kif2a antibody
    See all Kif2a primary antibodies
  • Description
    Rabbit polyclonal to Kif2a
  • SpecificityDetects Kinesin 2 (Kif2a) from mouse tissues.
  • Tested applicationsSuitable for: WBmore details
  • Species reactivity
    Reacts with: Mouse
    Predicted to work with: Rat, Chicken, Cow, Human, Xenopus laevis
  • Immunogen

    Synthetic peptide corresponding to Mouse Kif2a aa 1-11.
    Sequence:

    MVTSLNEDNES


    (Peptide available as ab4992)

  • Positive control
    • Mouse brain homogenate.

Properties

Associated products

Applications

Our Abpromise guarantee covers the use of ab3475 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/200. Detects a band of approximately 95 kDa (predicted molecular weight: 79 kDa).Can be blocked with KLC1 peptide (ab4992).

This antibody detects a ~95 kDa protein representing KIF 2 from mouse brain homogenate.

Target

  • FunctionPlus end-directed microtubule-dependent motor required for normal brain development. May regulate microtubule dynamics during axonal growth. Required for normal progression through mitosis. Required for normal congress of chromosomes at the metaphase plate. Required for normal spindle dynamics during mitosis. Promotes spindle turnover. Implicated in formation of bipolar mitotic spindles. Has microtubule depolymerization activity.
  • Sequence similaritiesBelongs to the kinesin-like protein family. MCAK/KIF2 subfamily.
    Contains 1 kinesin-motor domain.
  • Cellular localizationCytoplasm. Cytoplasm > cytoskeleton > centrosome. Cytoplasm > cytoskeleton > spindle pole. Cytoplasm > cytoskeleton > spindle. Localized to the spindle microtubules and spindle poles from prophase to metaphase. Efficient targeting to spindle microtubules and spindle poles requires the kinase activity of PLK1. Recruited to mitotic spindles by interaction with PSRC1.
  • Information by UniProt
  • Database links
  • Alternative names
    • CDCBM3 antibody
    • HK2 antibody
    • KIF2 antibody
    • KIF2A antibody
    • KIF2A_HUMAN antibody
    • Kinesin 2 antibody
    • Kinesin heavy chain 2 antibody
    • Kinesin heavy chain member 2 antibody
    • Kinesin heavy chain member 2A antibody
    • Kinesin like protein KIF2A antibody
    • Kinesin-2 antibody
    • Kinesin-like protein KIF2A antibody
    • KNS2 antibody
    • M Kinesin antibody
    see all

References for Anti-Kif2a antibody (ab3475)

ab3475 has not yet been referenced specifically in any publications.

Product Wall

Thank you for contacting us and for your interest in our products. I am sorry to confirm that as far as we are aware, ab3475 Kif2a antibody has not been tested in IHC-P.  All tested and guaranteed applications and species are specified on our datasheet...

Read More

Thank you for your comment. We will update and change the name of this antibody shortly. The name will be: Kinesin, Heavy Chain, 2 (KIF2).

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"