Overview

  • Product nameAnti-KIF3A antibody [K2.4]
    See all KIF3A primary antibodies
  • Description
    Mouse monoclonal [K2.4] to KIF3A
  • Specificityab24626 appears to react with epitopes on the 85 subunit (KIF3A) of kinesin II lying outside the conserved motor domain.
  • Tested applicationsSuitable for: Blocking, ICC/IF, WBmore details
  • Species reactivity
    Reacts with: Rat, Xenopus laevis, Sea Urchin
    Predicted to work with: all Mammals
  • Immunogen

    Full length native protein (purified)- kinesin II purified from unfertilized sea urchin egg cytosol.

  • General notes


    The antibody blocks ciliogenesis in urchin eggs.

Properties

Applications

Our Abpromise guarantee covers the use of ab24626 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
Blocking Use at an assay dependent dilution. It blocks ciliogenesis in urchin eggs.
ICC/IF Use at an assay dependent dilution.
WB 1/1000. Predicted molecular weight: 85-95 kDa.

Target

  • FunctionMicrotubule-based anterograde translocator for membranous organelles. Plus end-directed microtubule sliding activity in vitro.
  • Sequence similaritiesBelongs to the kinesin-like protein family. Kinesin II subfamily.
    Contains 1 kinesin-motor domain.
  • Cellular localizationCytoplasm > cytoskeleton.
  • Information by UniProt
  • Database links
  • Alternative names
    • KIF 3 antibody
    • KIF 3A antibody
    • KIF3 antibody
    • Kif3a antibody
    • KIF3A_HUMAN antibody
    • Kifl antibody
    • Kinesin family member 3A antibody
    • Kinesin family protein 3 antibody
    • Kinesin family protein 3A antibody
    • Kinesin like protein KIF 3A antibody
    • Kinesin like protein KIF3A antibody
    • Kinesin-like protein KIF3A antibody
    • Kns3 antibody
    • Microtubule plus end directed kinesin motor 3A antibody
    • Microtubule plus end-directed kinesin motor 3A antibody
    see all

Anti-KIF3A antibody [K2.4] images

  • Immunofluorescence analysis of rat hippocampal neurons, staining KIF3A with ab24626 at 1/500 dilution.

    Neurons were fixed in paraformaldehyde at 4°C for 20 minutes before incubation with the primary antibody. An AlexaFluor®-conjugated anti-mouse IgG was used as the secondary antibody (1/1000).

References for Anti-KIF3A antibody [K2.4] (ab24626)

This product has been referenced in:
  • Schwamborn JC  et al. The interaction of mPar3 with the ubiquitin ligase Smurf2 is required for the establishment of neuronal polarity. J Biol Chem 282:35259-68 (2007). WB, IF ; Rat . Read more (PubMed: 17906294) »

See 1 Publication for this product

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"