FunctionKinesin is a microtubule-associated force-producing protein that may play a role in organelle transport.
Tissue specificityHighest expression in brain, prostate and testis, and moderate expression in kidney, small intestine and ovary.
Sequence similaritiesBelongs to the kinesin-like protein family. Kinesin subfamily. Contains 1 kinesin-motor domain.
DomainComposed of three structural domains: a large globular N-terminal domain which is responsible for the motor activity of kinesin (it hydrolyzes ATP and binds microtubule), a central alpha-helical coiled coil domain that mediates the heavy chain dimerization; and a small globular C-terminal domain which interacts with other proteins (such as the kinesin light chains), vesicles and membranous organelles.