Overview

  • Product nameAnti-Kir2.2 antibody
    See all Kir2.2 primary antibodies
  • Description
    Rabbit polyclonal to Kir2.2
  • Tested applicationsSuitable for: IHC-Pmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    antigen sequence: RCSAKDLVEN KFLLPSANSF CYENELAFLS RDEEDEADGD QDGRSRDGLS PQARHDFDRL QAGGGVLEQR PYRRESEI, corresponding to amino acids 356-433 of Human Kir2.2

  • Positive control
    • Human kidney tissue.

Properties

  • FormLiquid
  • Storage instructionsShipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid repeated freeze / thaw cycles.
  • Storage bufferpH: 7.20
    Preservative: 0.02% Sodium azide
    Constituents: 59% PBS, 40% Glycerol
  • Concentration information loading...
  • PurityImmunogen affinity purified
  • ClonalityPolyclonal
  • IsotypeIgG
  • Research areas

Associated products

Applications

Our Abpromise guarantee covers the use of ab121905 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-P 1/200 - 1/500. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.

Target

  • FunctionProbably participates in establishing action potential waveform and excitability of neuronal and muscle tissues. Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it. Their voltage dependence is regulated by the concentration of extracellular potassium; as external potassium is raised, the voltage range of the channel opening shifts to more positive voltages. The inward rectification is mainly due to the blockage of outward current by internal magnesium. Can be blocked by extracellular barium and cesium.
  • Sequence similaritiesBelongs to the inward rectifier-type potassium channel (TC 1.A.2.1) family. KCNJ12 subfamily.
  • Cellular localizationMembrane.
  • Information by UniProt
  • Database links
  • Alternative names
    • ATP sensitive inward rectifier potassium channel 12 antibody
    • ATP-sensitive inward rectifier potassium channel 12 antibody
    • hIRK antibody
    • Human high conductance inward rectifier potassium channel alpha antibody
    • Inward rectifier K antibody
    • Inward rectifier K(+) channel Kir2.2 antibody
    • Inward rectifier K(+) channel Kir2.2v antibody
    • inwardly rectifying subfamily J member 12 antibody
    • IRK-2 antibody
    • IRK12_HUMAN antibody
    • IRK2 antibody
    • KCNJ12 antibody
    • kcnj12x antibody
    • KCNJN1 antibody
    • Kir2.2v antibody
    • Potassium channel antibody
    • Potassium channel inwardly rectifying subfamily J member 12 antibody
    • Potassium inwardly rectifying channel subfamily J member 12 antibody
    • Potassium inwardly rectifying channel,subfamily J inhibitor 1 antibody
    see all

Anti-Kir2.2 antibody images

  • ab121905 at 1/300 dilution staining Kir2.2 in Paraffin-embedded Human Kidney tissue by Immunohistochemistry.

References for Anti-Kir2.2 antibody (ab121905)

ab121905 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"