Overview

  • Product name
    Anti-KIR2.3 antibody
  • Description
    Rabbit polyclonal to KIR2.3
  • Tested applications
    Suitable for: WBmore details
  • Species reactivity
    Reacts with: Mouse, Human
    Predicted to work with: Rat
  • Immunogen

    Synthetic peptide derived from an internal region of Human KIR2.3

  • Positive control
    • 293 and NIH3T3 cell lysates

Properties

  • Form
    Liquid
  • Storage instructions
    Shipped at 4°C. Store at -20°C. Stable for 12 months at -20°C.
  • Storage buffer
    pH: 7.40
    Preservative: 0.02% Sodium azide
    Constituents: PBS, 0.88% Sodium chloride, 50% Glycerol
  • Concentration information loading...
  • Purity
    Immunogen affinity purified
  • Clonality
    Polyclonal
  • Isotype
    IgG
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab110701 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/500 - 1/1000. Predicted molecular weight: 50 kDa.

Target

  • Function
    This receptor is controlled by G proteins. Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it. Their voltage dependence is regulated by the concentration of extracellular potassium; as external potassium is raised, the voltage range of the channel opening shifts to more positive voltages. The inward rectification is mainly due to the blockage of outward current by internal magnesium. Can be blocked by extracellular barium and cesium.
  • Tissue specificity
    Heart, skeletal muscle, and several different brain regions including the hippocampus.
  • Sequence similarities
    Belongs to the inward rectifier-type potassium channel (TC 1.A.2.1) family. KCNJ4 subfamily.
  • Domain
    The Val/Gly/Ala/Pro stretch may have a functional role in the conductance or permeation properties.
  • Cellular localization
    Cell membrane. Cytoplasmic vesicle membrane. TAX1BP3 binding promotes dissociation of KCNJ4 from LIN7 famaly members and KCNJ4 internalization.
  • Information by UniProt
  • Database links
  • Alternative names
    • Hippocampal inward rectifier antibody
    • Hippocampal inward rectifier potassium channel antibody
    • HIR antibody
    • HIRK2 antibody
    • HRK1 antibody
    • Inward rectifier K(+) channel Kir2.3 antibody
    • Inward rectifier K+ channel Kir2.3 antibody
    • Inward rectifier potassium channel 4 antibody
    • Inward rectifier potassium channel Kir 2.3 antibody
    • inwardly rectifying subfamily J member 4 antibody
    • IRK-3 antibody
    • IRK3 antibody
    • IRK4_HUMAN antibody
    • KCNJ 4 antibody
    • Kcnj4 antibody
    • Kir2.3 antibody
    • MGC142066 antibody
    • MGC142068 antibody
    • OTTHUMP00000028922 antibody
    • Potassium channel antibody
    • Potassium channel inwardly rectifying subfamily J member 4 antibody
    • Potassium inwardly rectifying channel J4 antibody
    • Potassium inwardly rectifying channel subfamily J member 4 antibody
    see all

Images

  • All lanes : Anti-KIR2.3 antibody (ab110701) at 1/500 dilution

    Lane 1 : 293 cell lysate
    Lane 2 : NIH3T3 cell lysate
    Lane 3 : NIH3T3 cell lysate with blocking peptide at 10 µg

    Lysates/proteins at 30 µg per lane.


    Predicted band size : 50 kDa

References

ab110701 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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