Anti-KIR2DL1 + KIR2DL3 + KIR2DL4 + KIR2DS4 antibody [2H6] (ab26251)

Overview

  • Product name
    Anti-KIR2DL1 + KIR2DL3 + KIR2DL4 + KIR2DS4 antibody [2H6]
    See all KIR2DL1 + KIR2DL3 + KIR2DL4 + KIR2DS4 primary antibodies
  • Description
    Mouse monoclonal [2H6] to KIR2DL1 + KIR2DL3 + KIR2DL4 + KIR2DS4
  • Specificity
    This antibody recognises KIR2DL1, KIR2DL3, KIR2DL4 and KIR2DS4, members of killer cell immunoglobulin like receptor family.
  • Tested applications
    Suitable for: ELISA, WBmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Recombinant human KIR2D purified from E. coli.

  • Positive control
    • Human recombinant proteins KIR2DL1, KIR2DL3 and KIR2DL4.

Properties

  • Form
    Liquid
  • Storage instructions
    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term.
  • Storage buffer
    Preservative: 0.02% Thimerosal (merthiolate).
    Constituents: PBS.
  • Concentration information loading...
  • Purity
    Protein A purified
  • Clonality
    Monoclonal
  • Clone number
    2H6
  • Myeloma
    Sp2/0
  • Isotype
    IgG2b
  • Light chain type
    kappa
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab26251 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
ELISA Use at an assay dependent dilution.
WB 1/500 - 1/2000.

Target

  • Relevance
    KIRs are human natural killer (NK) cell receptors for MHC class I molecules. Most inhibit the activity of NK cells thus preventing cell lysis. Two main families of receptors for HLA class I have been discovered on human NK cells: Killer cell Immunoglobulin-like receptors (KIR) and CD94/NKG2 heterodimers. The KIR receptors are an extremely diverse family of receptors. In addition to receptors for HLA, NK cells also express pattern recognition receptors e.g. TLRs and Nod proteins.
  • Cellular localization
    Cell Membrane
  • Database links
  • Alternative names
    • CD158D antibody
    • CD158I antibody
    • G9P antibody
    • Killer cell Ig like receptors antibody
    • Killer cell immunoglobulin like receptor 2DL3 antibody
    • KKA3 antibody
    • Natural killer cell inhibitory receptor antibody
    • NKAT antibody
    • NKAT1 antibody
    • NKAT2 antibody
    • NKAT8 antibody
    • p58 NK receptor antibody
    see all

Images

  • All lanes : Anti-KIR2DL1 + KIR2DL3 + KIR2DL4 + KIR2DS4 antibody [2H6] (ab26251) at 1/500 dilution

    Lane 1 : Extracellular domain of KIR2DL1(23-223aa) (20ng)
    Lane 2 : Extracellular domain of KIR2DL3(23-223aa) (20ng)
    Lane 3 : Extracellular domain of KIR2DL4(44-202aa) (20ng)

    Secondary
    Goat anti-mouse conjugated to HRP
    Developed using the ECL technique

References

ab26251 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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