Recombinant
RabMAb

Anti-KIR2DL2 antibody [EPR8825] - C-terminal (ab179827)

Overview

  • Product name
    Anti-KIR2DL2 antibody [EPR8825] - C-terminal
    See all KIR2DL2 primary antibodies
  • Description
    Rabbit monoclonal [EPR8825] to KIR2DL2 - C-terminal
  • Tested applications
    Suitable for: Flow Cyt, WBmore details
    Unsuitable for: ICC/IF,IHC-P or IP
  • Species reactivity
    Reacts with: Mouse, Rat, Human
  • Immunogen

    Synthetic peptide (the amino acid sequence is considered to be commercially sensitive) within Human KIR2DL2 aa 300 to the C-terminus (Cysteine residue). The exact sequence is proprietary.
    Database link: P43627

  • Positive control
    • Hut-78, MOLT4, Jurkat and HeLa cell lysates; Jurkat cells.
  • General notes

    This product is a recombinant rabbit monoclonal antibody.

    Our RabMAb® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMab® patents

Properties

Applications

Our Abpromise guarantee covers the use of ab179827 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
Flow Cyt 1/10 - 1/100. ab172730-Rabbit monoclonal IgG, is suitable for use as an isotype control with this antibody.
WB 1/1000 - 1/5000. Detects a band of approximately 58 kDa (predicted molecular weight: 38 kDa).
  • Application notes
    Is unsuitable for ICC/IF,IHC-P or IP.
  • Target

    • Function
      Receptor on natural killer (NK) cells for HLA-C alleles. Inhibits the activity of NK cells thus preventing cell lysis.
    • Sequence similarities
      Belongs to the immunoglobulin superfamily.
      Contains 2 Ig-like C2-type (immunoglobulin-like) domains.
    • Cellular localization
      Cell membrane.
    • Information by UniProt
    • Database links
    • Alternative names
      • CD158 antigen-like family member B1 antibody
      • CD158b antibody
      • CD158b1 antibody
      • KI2L2_HUMAN antibody
      • Killer cell immunoglobulin like receptor two domains long cytoplasmic tail 2 antibody
      • Killer cell immunoglobulin-like receptor 2DL2 antibody
      • KIR2DL2 antibody
      • MHC class I NK cell receptor antibody
      • Natural killer-associated transcript 6 antibody
      • NKAT 6 antibody
      • NKAT-6 antibody
      • NKAT6 antibody
      • p58 natural killer cell receptor clone CL-43 antibody
      • p58 NK receptor CL-43 antibody
      • p58.2 antibody
      see all

    Images

    • Flow cytometric analysis of permeabilized Jurkat cells labeling KIR2DL2 with ab179827 at 1/10 dilution (red) or a rabbit IgG negative (green).

    • All lanes : Anti-KIR2DL2 antibody [EPR8825] - C-terminal (ab179827) at 1/1000 dilution

      Lane 1 : HuT-78 cell lysate
      Lane 2 : MOLT4 cell lysate
      Lane 3 : Jurkat cell lysate
      Lane 4 : HeLa cell lysate

      Secondary
      Goat anti-rabbit HRP at 1/2000 dilution

      Predicted band size : 38 kDa

    References

    ab179827 has not yet been referenced specifically in any publications.

    Customer reviews and Q&As

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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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