Anti-KIR5.1 (phospho S416) antibody (ab62453)

Overview

  • Product nameAnti-KIR5.1 (phospho S416) antibody
    See all KIR5.1 primary antibodies
  • Description
    Rabbit polyclonal to KIR5.1 (phospho S416)
  • Specificityab62453 detects endogenous levels of KIR5.1 only when phosphorylated at serine 416.
  • Tested applicationsSuitable for: IHC-P, ICC/IF, ELISAmore details
  • Species reactivity
    Reacts with: Mouse, Human
    Predicted to work with: Rat
  • Immunogen

    Synthetic phosphopeptide derived from human KIR5.1 around the phosphorylation site of serine 416 (M-E-SP-Q-M).

  • Positive control
    • IHC-P: Human brain tissue IF: and HeLa cells

Properties

  • FormLiquid
  • Storage instructionsShipped at 4°C. Store at -20°C. Stable for 12 months at -20°C.
  • Storage bufferPreservative: 0.02% Sodium Azide
    Constituents: 50% Glycerol, PBS (without Mg2+ and Ca2+), 150mM Sodium chloride, pH 7.4
  • Concentration information loading...
  • PurityImmunogen affinity purified
  • Purification notesab62453 was affinity purified from rabbit antiserum by affinity chromatography using epitope specific phosphopeptide. The antibody against non phosphopeptide was removed by chromatography using non phosphopeptide corresponding to the phosphorylation site.
  • ClonalityPolyclonal
  • IsotypeIgG
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab62453 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-P 1/50 - 1/100.
ICC/IF 1/500 - 1/1000.
ELISA 1/5000.

Target

  • RelevanceKIR5.1 is one of 20 members of the inwardly rectifying potassium (Kir) channel family. Due to its expression in kidney, pancreas and thyroid gland, it has been suggested that human KIR5.1 may be involved in the regulation of fluid and pH balance, thus making it a potential therapeutic target for hypertension, renal failure, or pancreatic disease.
  • Cellular localizationMembrane; Multi pass membrane protein.
  • Database links
  • Alternative names
    • 6430410F18Rik antibody
    • AI132396 antibody
    • BIR9 antibody
    • Inward rectifier K channel Kir5.1 antibody
    • Inward rectifier K(+) channel Kir5.1 antibody
    • Inward rectifier potassium channel 16 antibody
    • IRK16 antibody
    • IRKG antibody
    • KCNJ16 antibody
    • MGC33717 antibody
    • Potassium channel inwardly rectifying subfamily J member 16 antibody
    • Potassium inwardly rectifying channel subfamily J member 16 antibody
    • RP23-218O16.1 antibody
    see all

Anti-KIR5.1 (phospho S416) antibody images

  • ab62453, at 1/50 dilution, staining KIR5.1 in paraffin embedded human brain tissue by Immunohistochemistry in the absence or presence of the immunising peptide.
  • ab62453, at a 1/1000 dilution, staining KIR5.1 in HeLa cells by Immunofluorescence, in the absence or presence of the immunising peptide.

References for Anti-KIR5.1 (phospho S416) antibody (ab62453)

ab62453 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"