Overview

  • Product nameAnti-Kir6.2 antibody
    See all Kir6.2 primary antibodies
  • Description
    Rabbit polyclonal to Kir6.2
  • Tested applicationsSuitable for: WBmore details
  • Species reactivity
    Reacts with: Mouse, Human
  • Immunogen

    Synthetic peptide conjugated to KLH, selected from the N terminal region of Human Kir6.2.

  • Positive control
    • Mouse stomach tissue lysate

Properties

Applications

Our Abpromise guarantee covers the use of ab95317 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/100 - 1/500. Predicted molecular weight: 44 kDa.

Target

  • RelevanceATP-sensitive potassium (K(ATP)) channels are found in endocrine cells, neurons and both smooth and striated muscle, where they play an important role in controlling insulin secretion and vascular tone, and protect neurons under metabolic stress. Kir6.2 is a member of the inward rectifier potassium channel family, which is characterised by a greater tendency to allow potassium flow into the cell rather than out of it. It associates with the sulphonylurea receptor SUR1/ABCC8 to form a subfamily of K(ATP) channels that, when mutated or misregulated, are associated with forms of hyperinsulinemic hypoglycemia, neonatal diabetes, or pre-disposition to type 2 diabetes mellitus.
  • Cellular localizationCell Membrane; Multi-pass membrane protein
  • Database links
  • Alternative names
    • ATP sensitive inward rectifier potassium channel 11 antibody
    • Beta cell inward rectifier subunit antibody
    • BIR antibody
    • HHF 2 antibody
    • HHF2 antibody
    • IKATP antibody
    • Inward rectifier K(+) channel Kir6.2 antibody
    • Inwardly rectifying potassium channel KIR6.2 antibody
    • IRK 11 antibody
    • IRK11 antibody
    • KCNJ11 antibody
    • Kir 6.2 antibody
    • Kir6.2 antibody
    • MGC133230 antibody
    • PHHI antibody
    • Potassium channel inwardly rectifing subfamily J member 11 antibody
    • Potassium channel, inwardly rectifying subfamily J member 11 antibody
    • Potassium inwardly rectifying channel J11 antibody
    • TNDM 3 antibody
    • TNDM3 antibody
    see all

Anti-Kir6.2 antibody images

  • Anti-Kir6.2 antibody (ab95317) at 1/100 dilution (in TTBS/1% NFDM for 1 hr. at room temperature) + mouse stomach tissue lysate at 35 µg

    Secondary
    Enzyme-linked secondary antibody (typically horseradish peroxidase or alkaline phosphatase) in TTBS/1% NFDM for 30 min. at room temperature.

    Predicted band size : 44 kDa

References for Anti-Kir6.2 antibody (ab95317)

ab95317 has not yet been referenced specifically in any publications.

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