Anti-KIRREL antibody - C-terminal (ab156084)

Overview

  • Product name
    Anti-KIRREL antibody - C-terminal
    See all KIRREL primary antibodies
  • Description
    Rabbit polyclonal to KIRREL - C-terminal
  • Tested applications
    Suitable for: WBmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Synthetic peptide conjugated to KLH, corresponding to a region within C-terminal amino acids 505-534 of Human KIRREL (NP_060710.3).

  • Positive control
    • MDA-MB231 cell line lysate

Properties

Applications

Our Abpromise guarantee covers the use of ab156084 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/100 - 1/500. Predicted molecular weight: 84 kDa.

Target

  • Function
    Plays a significant role in the normal development and function of the glomerular permeability. Signaling protein that needs the presence of TEC kinases to fully trans-activate the transcription factor AP-1.
  • Tissue specificity
    Abundantly expressed in kidney. Specifically expressed in podocytes of kidney glomeruli.
  • Sequence similarities
    Belongs to the immunoglobulin superfamily.
    Contains 5 Ig-like C2-type (immunoglobulin-like) domains.
  • Post-translational
    modifications
    Phosphorylation probably regulates the interaction with NSH2.
    N-glycosylated.
  • Cellular localization
    Cell membrane. Predominantly located at podocyte slit diaphragm.
  • Information by UniProt
  • Database links
  • Alternative names
    • FLJ10845 antibody
    • Kin of IRRE like (Drosophila) antibody
    • Kin of IRRE like antibody
    • Kin of IRRE like protein 1 antibody
    • Kin of IRRE-like protein 1 antibody
    • Kin of irregular chiasm like protein 1 antibody
    • Kin of irregular chiasm-like protein 1 antibody
    • KIRR1_HUMAN antibody
    • Kirrel antibody
    • MGC129542 antibody
    • MGC129543 antibody
    • NEPH 1 antibody
    • NEPH1 antibody
    • Nephrin like protein 1 antibody
    • Nephrin related antibody
    • Nephrin-like protein 1 antibody
    • OTTHUMP00000024055 antibody
    see all

Images

  • Anti-KIRREL antibody - C-terminal (ab156084) at 1/100 dilution + MDA-MB231 cell line lysate at 35 µg

    Predicted band size : 84 kDa

References

ab156084 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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