Overview

Description

  • NatureSynthetic
  • Amino Acid Sequence
    • SequenceFLEVGTLERYTVERTNSGSGVLSTLTINNVMEADFQTHYNCTAWNSFGPG
    • Molecular weight66 kDa

Associated products

Specifications

Our Abpromise guarantee covers the use of ab109278 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    Blocking - Blocking peptide for Anti-KIRREL antibody (ab82804)

  • FormLiquid
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

General Info

  • Alternative names
    • FLJ10845
    • Kin of IRRE like
    • Kin of IRRE like (Drosophila)
    • Kin of IRRE like protein 1
    • Kin of IRRE-like protein 1
    • Kin of irregular chiasm like protein 1
    • Kin of irregular chiasm-like protein 1
    • KIRR1_HUMAN
    • Kirrel
    • MGC129542
    • MGC129543
    • NEPH 1
    • NEPH1
    • Nephrin like protein 1
    • Nephrin related
    • Nephrin-like protein 1
    • OTTHUMP00000024055
    see all
  • FunctionPlays a significant role in the normal development and function of the glomerular permeability. Signaling protein that needs the presence of TEC kinases to fully trans-activate the transcription factor AP-1.
  • Tissue specificityAbundantly expressed in kidney. Specifically expressed in podocytes of kidney glomeruli.
  • Sequence similaritiesBelongs to the immunoglobulin superfamily.
    Contains 5 Ig-like C2-type (immunoglobulin-like) domains.
  • Post-translational
    modifications
    Phosphorylation probably regulates the interaction with NSH2.
    N-glycosylated.
  • Cellular localizationCell membrane. Predominantly located at podocyte slit diaphragm.
  • Information by UniProt

References for KIRREL peptide (ab109278)

ab109278 has not yet been referenced specifically in any publications.

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