The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
1/100 - 1/500. Detects a band of approximately 47 kDa (predicted molecular weight: 47 kDa).
FunctionUpon serum stimulation, phosphorylates CDKN1B/p27Kip1, thus controlling CDKN1B subcellular location and cell cycle progression in G1 phase. May be involved in trafficking and/or processing of RNA.
Tissue specificityWidely expressed, with highest levels in skeletal muscle, kidney, placenta and peripheral blood leukocytes.
Sequence similaritiesBelongs to the protein kinase superfamily. Ser/Thr protein kinase family. Contains 1 protein kinase domain. Contains 1 RRM (RNA recognition motif) domain.
kinase interacting with leukemia-associated gene (stathmin) antibody
Kinase interacting with stathmin antibody
KIS protein kinase antibody
Serine threonine protein kinase Kist antibody
Serine/threonine-protein kinase Kist antibody
U2AF homology motif (UHM) kinase 1 antibody
U2AF homology motif kinase 1 antibody
Anti-KIST antibody images
Western blot - KIST antibody (ab38292)
All lanes : Anti-KIST antibody (ab38292)
Lane 1 : K562 cell lysate Lane 2 : Mouse liver tissue lysate
Predicted band size : 47 kDa Observed band size : 47 kDa Additional bands at : 60 kDa,70 kDa. We are unsure as to the identity of these extra bands.
References for Anti-KIST antibody (ab38292)
This product has been referenced in:
Ranchal I et al. The reduction of cell death and proliferation by p27(Kip1) minimizes DNA damage in an experimental model of genotoxicity. Int J Cancer125:2270-80 (2009).
Read more (PubMed: 19672859) »
Bristow GC et al. Expression of kinase interacting with stathmin (KIS, UHMK1) in human brain and lymphoblasts: Effects of schizophrenia and genotype. Brain Res1301:197-206 (2009).
Read more (PubMed: 19747464) »