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Learn about current miRNA technologies and applications with our selection of miRNA content.
The search for miRNA biomarkers for a range of diseases is well underway. We review why miRNAs have such potential as biomarkers and review current literature in the field. Read the article now.
Our miRNAs as biomarkers series examines the role of miRNAs in six specific areas: cancer, cardiovascular disease, immune system diseases, liver toxicity and disease, nervous system disorders and stem cells and differentiation.
In recent years, much attention has been focused on the regulatory activity of a class of RNAs known as microRNAs (miRNAs). Although there is now widespread interest in miRNAs, this wasn't always the case. Indeed, these short (~22 bp) non-coding RNA sequences were only discovered in 1993 by Victor Ambros and colleagues.
Research suggests that microRNAs travel around the body contained within exosomes. In this article, we examine recent progress in this exciting field.
Although bioinformatics plays a big part in identifying putative miRNAs, they also need to be experimentally verified in the lab. A range of techniques have been developed to overcome the challenges of miRNA profiling and here we review the most popular methods currently in use.
Our compilation of over 30 miRNA research tools includes databases, target predictors and deep sequencing tools.