• Product name
  • Description
    Goat polyclonal to KLF2
  • Tested applications
    Suitable for: WBmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Mouse, Rat, Cow, Dog, Pig, Xenopus laevis
  • Immunogen

    Synthetic peptide: ALSEPILPSFST, corresponding to N terminal amino acids 2-13 of Human KLF2.

  • Positive control
    • Human heart lysate



Our Abpromise guarantee covers the use of ab17008 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
  • Application notes
    ELISA: 1/32000.
    WB: Use at a concentration of 1.5 - 3 µg/ml. Detects a band of approximately 40 kDa (predicted molecular weight: 41 kDa) from human heart lysates.

    Not tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • Target

    • Function
      Binds to the CACCC box in the beta-globin gene promoter and activates transcription.
    • Sequence similarities
      Belongs to the krueppel C2H2-type zinc-finger protein family.
      Contains 3 C2H2-type zinc fingers.
    • Post-translational
      Ubiquitinated. Polyubiquitination involves WWP1 and leads to proteasomal degradation of this protein.
    • Cellular localization
    • Information by UniProt
    • Database links
    • Alternative names
      • KLF 2 antibody
      • Klf2 antibody
      • KLF2_HUMAN antibody
      • Krueppel-like factor 2 antibody
      • Kruppel like factor 2 antibody
      • Kruppel like factor antibody
      • Kruppel like factor LKLF antibody
      • Kruppel-like factor 2 (lung) antibody
      • Lklf antibody
      • Lung krueppel like factor antibody
      • Lung krueppel-like factor antibody
      • Lung Kruppel like zinc finger transcription factor antibody
      see all


    • Predicted band size : 41 kDa

      ab17008 at 1.5µg/ml detecting KLF2 from human heart lysate by Western blot. 35µg of total protein was loaded per lane. Primary antibody was incubated for 1 hour. The blot was detected using chemiluminescence.


    This product has been referenced in:
    • Zou K  et al. Krüppel-like factor 2 promotes cell proliferation in hepatocellular carcinoma through up-regulation of c-myc. Cancer Biol Ther 17:20-6 (2016). Read more (PubMed: 26853883) »
    • Tuomisto TT  et al. Simvastatin has an anti-inflammatory effect on macrophages via upregulation of an atheroprotective transcription factor, Kruppel-like factor 2. Cardiovasc Res 78:175-84 (2008). Read more (PubMed: 18192240) »

    See all 2 Publications for this product

    Customer reviews and Q&As

    Thank you for your enquiry. Since this KLF2 is a transcription factor, it is expected to reside in the nucleus. Therefore, it will recognize the intracellular domain. I hope this information will be helpful. If there is anything else that I ...

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    Thank you for your enquiry. No, this has not been specifically tested. The sequence of the peptide used as the immunogen is listed on the online datasheet and you can BLAST it (the BLAST link is on the online datasheet too) to see if it is likely to cr...

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    Thank you for taking the time to send us your protocol details, this was very useful for me to understand your problem. We have not tested this antibody in the same samples as yours; in our hands, our positive control of human heart lysate gave a s...

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    Thank you for your phone call and I'm sorry to hear that you are experiencing difficulty with ab17008. Would you be able to provide me with a detailed protocol? This will assist in helping to troubleshoot. It would be really helpful if you could cl...

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