Overview

  • Product nameAnti-KLF8 antibody
    See all KLF8 primary antibodies
  • Description
    Goat polyclonal to KLF8
  • Tested applicationsSuitable for: WBmore details
  • Species reactivity

    Predicted to work with: Human
  • Immunogen

    Synthetic peptide:

    VDMDKLINNLEVQ

    , corresponding to N terminal amino acids 2-14 of Human KLF8.

  • Positive control
    • Human Kidney lysate.
  • General notesPrincipal Names – KLF8; Kruppel-like factor 8; BKLF3; DXS741; ZNF741; zinc finger protein 741. Official Gene Symbol - KLF8. GenBank Accession Number – NP_009181. LocusLink ID - 11279 (human)

Properties

Applications

Our Abpromise guarantee covers the use of ab2747 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB
  • Application notesWestern Blot: Approx 50kDa band seen in Human Kidney lysate.
    Predicted molecular weight: 40 kDa.
    Recommended for use at 1.0-3.0µg/ml.
  • Target

    • FunctionTranscriptional repressor and activator. Binds to CACCC-boxes promoter elements. Also binds the GT-box of cyclin D1 promoter and mediates cell cycle progression at G(1) phase as a downstream target of focal adhesion kinase (FAK).
    • Tissue specificityUbiquitous.
    • Sequence similaritiesBelongs to the Sp1 C2H2-type zinc-finger protein family.
      Contains 3 C2H2-type zinc fingers.
    • Post-translational
      modifications
      Sumoylation at Lys-67 represses transcriptional activity and reduces cell cycle progression into the G(1) phase. Has no effect on subcellular location.
    • Cellular localizationNucleus.
    • Information by UniProt
    • Database links
    • Alternative names
      • Basic krueppel-like factor 3 antibody
      • BKLF3 antibody
      • DXS741 antibody
      • KLF8 antibody
      • KLF8_HUMAN antibody
      • Krueppel-like factor 8 antibody
      • Kruppel like factor 8 antibody
      • MGC138314 antibody
      • Zinc finger protein 741 antibody
      • ZNF741 antibody
      see all

    Anti-KLF8 antibody images

    References for Anti-KLF8 antibody (ab2747)

    ab2747 has not yet been referenced specifically in any publications.

    Product Wall

    There are currently no Abreviews or Questions for ab2747.
    Please use the links above to contact us or submit feedback about this product.

    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"