Overview

  • Product name
    Anti-KLRA2 antibody
  • Description
    Rabbit polyclonal to KLRA2
  • Tested applications
    Suitable for: ICC/IF, WB, IHC-Pmore details
  • Species reactivity
    Reacts with: Mouse, Rat
  • Immunogen

    14 amino acid synthetic peptide near the C-terminus of Mouse KLRA2

  • Positive control
    • Mouse spleen tissue lysate, Human spleen tissue

Properties

  • Form
    Liquid
  • Storage instructions
    Shipped at 4°C. Store at 4°C (stable for up to 12 months).
  • Storage buffer
    Preservative: 0.02% Sodium Azide
    Constituents: PBS
  • Concentration information loading...
  • Purity
    Immunogen affinity purified
  • Clonality
    Polyclonal
  • Isotype
    IgG
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab107510 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
ICC/IF Use a concentration of 20 µg/ml.
WB Use a concentration of 0.5 - 1 µg/ml. Predicted molecular weight: 34 kDa.
IHC-P Use a concentration of 2.5 µg/ml.

Target

  • Relevance
    KLRA2 (also known as Ly49B) is a member of the LY49 family of receptors in Natural Killer (NK) cells that bind to major histocompatibility complex (MHC) class 1. These proteins are classified as either activating or inhibitory receptors based on whether they possess an immunoreceptor tyrosine-based inhibitory motif (ITIM) in their cytoplasmic region (for inhibitory receptors), or an immunoreceptor tyrosine-based activation motif (ITAM) that transmits activating signals resulting in phosphorylation of several substrates. KLRA2 is thought to be an inhibitory receptor and associates with the protein tyrosine phosphatases SHP1, SHP2, and SHIP in transfected cells.
  • Cellular localization
    Membrane
  • Database links
  • Alternative names
    • Ly49-b antibody
    • Killer cell lectin-like receptor 2 antibody
    • Klra2 antibody
    • Ly-49b antibody
    • Ly49b antibody
    • Lymphocyte antigen 49b antibody
    • T-cell surface glycoprotein Ly-49B antibody
    see all

Images

  • Lane 1 : Anti-KLRA2 antibody (ab107510) at 0.5 µg/ml
    Lane 2 : Anti-KLRA2 antibody (ab107510) at 1 µg/ml

    Lane 1 : Mouse spleen tissue lysate
    Lane 2 : Mouse spleen tissue lysate

    Lysates/proteins at 15 µg per lane.


    Predicted band size : 34 kDa
  • Immunohistochemistry of KLRA2 in paraffin embedded mouse spleen tissue with ab107510 at 2.5 µg/ml.

References

ab107510 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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