Overview

  • Product nameAnti-KLRG1 antibody
    See all KLRG1 primary antibodies
  • Description
    Rabbit polyclonal to KLRG1
  • Tested applicationsSuitable for: WBmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Recombinant fragment, corresponding to a region within amino acids 1-184 of Human KLRG1 (NP_005801).

  • Positive control
    • HeLa whole cell lysate

Properties

  • FormLiquid
  • Storage instructionsShipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
  • Storage bufferPreservative: 0.01% Thimerosal (merthiolate)
    Constituents: 10% Glycerol, 0.1M Tris, 0.1M Glycine, pH 7.0
  • Concentration information loading...
  • PurityImmunogen affinity purified
  • ClonalityPolyclonal
  • IsotypeIgG
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab96317 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/500 - 1/3000. Predicted molecular weight: 22 kDa.

Target

  • FunctionPlays an inhibitory role on natural killer (NK) cells and T-cell functions upon binding to their non-MHC ligands. May mediate missing self recognition by binding to a highly conserved site on classical cadherins, enabling it to monitor expression of E-cadherin/CDH1, N-cadherin/CDH2 and R-cadherin/CDH4 on target cells.
  • Tissue specificityExpressed specifically on natural killer (NK) cells and T-cells, mainly CD8 T-cells.
  • Sequence similaritiesContains 1 C-type lectin domain.
  • DomainContains 1 copy of a cytoplasmic motif that is referred to as the immunoreceptor tyrosine-based inhibitor motif (ITIM). This motif is involved in modulation of cellular responses. Upon phosphorylation of ITIM motif KLRG1 associates with the two phosphatases PTPN11 and INPP5D.
  • Cellular localizationCell membrane.
  • Information by UniProt
  • Database links
  • Alternative names
    • 2F1 Ag antibody
    • 2F1 antibody
    • C type lectin domain family 15 member A antibody
    • C-type lectin domain family 15 member A antibody
    • CLEC15A antibody
    • ITIM containing receptor MAFA L antibody
    • ITIM-containing receptor MAFA-L antibody
    • Killer cell lectin like receptor G1 antibody
    • Killer cell lectin like receptor subfamily G member 1 antibody
    • Killer cell lectin-like receptor subfamily G member 1 antibody
    • KLRG 1 antibody
    • KLRG1 antibody
    • KLRG1 protein antibody
    • KLRG1_HUMAN antibody
    • MAFA 2F1 antibody
    • MAFA antibody
    • MAFA L antibody
    • MAFA like antibody
    • MAFA like receptor antibody
    • MAFA-like receptor antibody
    • MAFAL antibody
    • Mast cell function associated antigen (ITIM containing) antibody
    • Mast cell function associated antigen antibody
    • Mast cell function-associated antigen 2F1 antibody
    • Mast cell function-associated antigen antibody
    • Mast cell function-associated antigen, rat, homolog of antibody
    • MGC13600 antibody
    see all

Anti-KLRG1 antibody images

  • Anti-KLRG1 antibody (ab96317) at 1/1000 dilution + HeLa whole cell lysate at 30 µg

    Predicted band size : 22 kDa

References for Anti-KLRG1 antibody (ab96317)

ab96317 has not yet been referenced specifically in any publications.

Product Wall

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I have had a look at our catalogue and we don't indeed have an antibody for direct immunofluoresence which is predicted to work in human. Ab96317 as you have pointed out is the only anti-KLRG-1 antibody guaranteed...

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"