• Product name
    Anti-KLRG1 antibody [EPR11237]
    See all KLRG1 primary antibodies
  • Description
    Rabbit monoclonal [EPR11237] to KLRG1
  • Host species
  • Tested applications
    Suitable for: WBmore details
    Unsuitable for: Flow Cyt,ICC/IF,IHC-P or IP
  • Species reactivity
    Reacts with: Mouse, Rat, Human
  • Immunogen

    Synthetic peptide (the amino acid sequence is considered to be commercially sensitive) within Human KLRG1 aa 1-100. The exact sequence is proprietary.
    Database link: Q96E93

  • Positive control
    • Human thymus, HUT-78, THP1, Jurkat and Raji lysates.
  • General notes

    This product is a recombinant rabbit monoclonal antibody.

    Our RabMAb® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMab® patents


  • Form
  • Storage instructions
    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle.
  • Storage buffer
    Preservative: 0.01% Sodium azide
    Constituents: 50% Glycerol, 0.05% BSA
  • Purity
    Tissue culture supernatant
  • Clonality
  • Clone number
  • Isotype
  • Research areas


Our Abpromise guarantee covers the use of ab170959 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/1000 - 1/5000. Predicted molecular weight: 22 kDa.
  • Application notes
    Is unsuitable for Flow Cyt,ICC/IF,IHC-P or IP.
  • Target

    • Function
      Plays an inhibitory role on natural killer (NK) cells and T-cell functions upon binding to their non-MHC ligands. May mediate missing self recognition by binding to a highly conserved site on classical cadherins, enabling it to monitor expression of E-cadherin/CDH1, N-cadherin/CDH2 and R-cadherin/CDH4 on target cells.
    • Tissue specificity
      Expressed specifically on natural killer (NK) cells and T-cells, mainly CD8 T-cells.
    • Sequence similarities
      Contains 1 C-type lectin domain.
    • Domain
      Contains 1 copy of a cytoplasmic motif that is referred to as the immunoreceptor tyrosine-based inhibitor motif (ITIM). This motif is involved in modulation of cellular responses. Upon phosphorylation of ITIM motif KLRG1 associates with the two phosphatases PTPN11 and INPP5D.
    • Cellular localization
      Cell membrane.
    • Information by UniProt
    • Database links
    • Alternative names
      • 2F1 Ag antibody
      • 2F1 antibody
      • C type lectin domain family 15 member A antibody
      • C-type lectin domain family 15 member A antibody
      • CLEC15A antibody
      • ITIM containing receptor MAFA L antibody
      • ITIM-containing receptor MAFA-L antibody
      • Killer cell lectin like receptor G1 antibody
      • Killer cell lectin like receptor subfamily G member 1 antibody
      • Killer cell lectin-like receptor subfamily G member 1 antibody
      • KLRG 1 antibody
      • KLRG1 antibody
      • KLRG1 protein antibody
      • KLRG1_HUMAN antibody
      • MAFA 2F1 antibody
      • MAFA antibody
      • MAFA L antibody
      • MAFA like antibody
      • MAFA like receptor antibody
      • MAFA-like receptor antibody
      • MAFAL antibody
      • Mast cell function associated antigen (ITIM containing) antibody
      • Mast cell function associated antigen antibody
      • Mast cell function-associated antigen 2F1 antibody
      • Mast cell function-associated antigen antibody
      • Mast cell function-associated antigen, rat, homolog of antibody
      • MGC13600 antibody
      see all


    • All lanes : Anti-KLRG1 antibody [EPR11237] (ab170959) at 1/1000 dilution

      Lane 1 : Human thymus lysate
      Lane 2 : HUT-78 lysate
      Lane 3 : THP1 lysate
      Lane 4 : Jurkat lysate
      Lane 5 : Raji lysate

      Lysates/proteins at 10 µg per lane.

      All lanes : Goat anti-rabbit HRP at 1/2000 dilution

      Developed using the ECL technique.

      Predicted band size: 22 kDa


    This product has been referenced in:
    • Müller-Durovic B  et al. Killer Cell Lectin-like Receptor G1 Inhibits NK Cell Function through Activation of Adenosine 5'-Monophosphate-Activated Protein Kinase. J Immunol 197:2891-9 (2016). Read more (PubMed: 27566818) »

    See 1 Publication for this product

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