Anti-KMT3C / SMYD2 antibody - N-terminal (ab71235)

Overview

  • Product name
    Anti-KMT3C / SMYD2 antibody - N-terminal
    See all KMT3C / SMYD2 primary antibodies
  • Description
    Rabbit polyclonal to KMT3C / SMYD2 - N-terminal
  • Tested applications
    Suitable for: ELISA, WBmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Synthetic peptide at the N terminal region of human KMT3C/ SMYD2 conjugated to KLH

  • Positive control
    • 293 cell lysate transiently transfected with the KMT3C / SMYD2 gene.

Properties

Applications

Our Abpromise guarantee covers the use of ab71235 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
ELISA 1/1000.
WB 1/50 - 1/100. Detects a band of approximately 50 kDa (predicted molecular weight: 50 kDa).

Target

  • Function
    Protein-lysine N-methyltransferase that methylates both histones and non-histone proteins. Specifically methylates histone H3 'Lys-4' (H3K4me) and dimethylates histone H3 'Lys-36' (H3K36me2). Has also methyltransferase activity toward non-histone proteins such as p53/TP53 and RB1. Monomethylates 'Lys-370' of p53/TP53, leading to decreased DNA-binding activity and subsequent transcriptional regulation activity of p53/TP53. Monomethylates 'Lys-860' of RB1/RB.
  • Sequence similarities
    Contains 1 MYND-type zinc finger.
    Contains 1 SET domain.
  • Cellular localization
    Cytoplasm > cytosol. Nucleus.
  • Information by UniProt
  • Database links
  • Alternative names
    • Histone methyltransferase SMYD2 antibody
    • HSKM B antibody
    • HSKM-B antibody
    • HSKMB antibody
    • KMT3C antibody
    • Lysine N-methyltransferase 3C antibody
    • MGC119305 antibody
    • N lysine methyltransferase SMYD2 antibody
    • N-lysine methyltransferase SMYD2 antibody
    • SET and MYND domain containing 2 antibody
    • SET and MYND domain containing protein 2 antibody
    • SET and MYND domain-containing protein 2 antibody
    • Smyd2 antibody
    • SMYD2_HUMAN antibody
    • Zinc finger MYND domain containing 14 antibody
    • ZMYND14 antibody
    see all

Images

  • All lanes : Anti-KMT3C / SMYD2 antibody - N-terminal (ab71235) at 1/50 dilution

    Lane 1 : 293 cell lysates (non transfected)
    Lane 2 : 293 cell lysates transiently transfected with the KMT3C / SMYD2 gene

    Lysates/proteins at 2 µg per lane.


    Predicted band size : 50 kDa
    Observed band size : 50 kDa

References

ab71235 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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