Anti-KMT3C / SMYD2 antibody - N-terminal (ab71235)

Overview

  • Product nameAnti-KMT3C / SMYD2 antibody - N-terminal
    See all KMT3C / SMYD2 primary antibodies
  • Description
    Rabbit polyclonal to KMT3C / SMYD2 - N-terminal
  • Tested applicationsSuitable for: ELISA, WBmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Synthetic peptide at the N terminal region of human KMT3C/ SMYD2 conjugated to KLH

  • Positive control
    • 293 cell lysate transiently transfected with the KMT3C / SMYD2 gene.

Properties

Applications

Our Abpromise guarantee covers the use of ab71235 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
ELISA 1/1000.
WB 1/50 - 1/100. Detects a band of approximately 50 kDa (predicted molecular weight: 50 kDa).

Target

  • FunctionProtein-lysine N-methyltransferase that methylates both histones and non-histone proteins. Specifically methylates histone H3 'Lys-4' (H3K4me) and dimethylates histone H3 'Lys-36' (H3K36me2). Has also methyltransferase activity toward non-histone proteins such as p53/TP53 and RB1. Monomethylates 'Lys-370' of p53/TP53, leading to decreased DNA-binding activity and subsequent transcriptional regulation activity of p53/TP53. Monomethylates 'Lys-860' of RB1/RB.
  • Sequence similaritiesContains 1 MYND-type zinc finger.
    Contains 1 SET domain.
  • Cellular localizationCytoplasm > cytosol. Nucleus.
  • Information by UniProt
  • Database links
  • Alternative names
    • Histone methyltransferase SMYD2 antibody
    • HSKM B antibody
    • HSKM-B antibody
    • HSKMB antibody
    • KMT3C antibody
    • Lysine N-methyltransferase 3C antibody
    • MGC119305 antibody
    • N lysine methyltransferase SMYD2 antibody
    • N-lysine methyltransferase SMYD2 antibody
    • SET and MYND domain containing 2 antibody
    • SET and MYND domain containing protein 2 antibody
    • SET and MYND domain-containing protein 2 antibody
    • Smyd2 antibody
    • SMYD2_HUMAN antibody
    • Zinc finger MYND domain containing 14 antibody
    • ZMYND14 antibody
    see all

Anti-KMT3C / SMYD2 antibody - N-terminal images

  • All lanes : Anti-KMT3C / SMYD2 antibody - N-terminal (ab71235) at 1/50 dilution

    Lane 1 : 293 cell lysates (non transfected)
    Lane 2 : 293 cell lysates transiently transfected with the KMT3C / SMYD2 gene

    Lysates/proteins at 2 µg per lane.


    Predicted band size : 50 kDa
    Observed band size : 50 kDa

References for Anti-KMT3C / SMYD2 antibody - N-terminal (ab71235)

ab71235 has not yet been referenced specifically in any publications.

Product Wall

There are currently no Abreviews or Questions for ab71235.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"