• Product nameAnti-KPNA6 antibody
    See all KPNA6 primary antibodies
  • Description
    Goat polyclonal to KPNA6
  • Tested applicationsSuitable for: WB, IHC-Pmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Mouse, Rat, Chicken, Cow, Dog, Pig, Cynomolgus monkey, Orangutan
  • Immunogen

    Peptide with sequence


    , corresponding to internal sequence amino acids 74-87 of human KPNA6 (NP_036448.1).

  • Positive control
    • Human skeletal muscle lysate.


  • FormLiquid
  • Storage instructionsShipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
  • Storage bufferPreservative: 0.02% Sodium Azide
    Constituents: 0.5% BSA, Tris saline, pH 7.3
  • Concentration information loading...
  • PurityImmunogen affinity purified
  • Purification notesPurified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
  • ClonalityPolyclonal
  • IsotypeIgG
  • Research areas


Our Abpromise guarantee covers the use of ab82149 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 0.1 - 0.3 µg/ml. Predicted molecular weight: 60 kDa. A customer reported that milk can significantly suppress antigen-antibody interaction on nitrocellulose membrane in WB.
IHC-P Use a concentration of 3 - 6 µg/ml.


  • FunctionFunctions in nuclear protein import as an adapter protein for nuclear receptor KPNB1. Binds specifically and directly to substrates containing either a simple or bipartite NLS motif. Docking of the importin/substrate complex to the nuclear pore complex (NPC) is mediated by KPNB1 through binding to nucleoporin FxFG repeats and the complex is subsequently translocated through the pore by an energy requiring, Ran-dependent mechanism. At the nucleoplasmic side of the NPC, Ran binds to importin-beta and the three components separate and importin-alpha and -beta are re-exported from the nucleus to the cytoplasm where GTP hydrolysis releases Ran from importin. The directionality of nuclear import is thought to be conferred by an asymmetric distribution of the GTP- and GDP-bound forms of Ran between the cytoplasm and nucleus.
  • Tissue specificityWidely expressed.
  • Sequence similaritiesBelongs to the importin alpha family.
    Contains 10 ARM repeats.
    Contains 1 IBB domain.
  • Information by UniProt
  • Database links
  • FormCellular location: cytoplasm; nucleus.
  • Alternative names
    • FLJ11249 antibody
    • IMA7_HUMAN antibody
    • Importin alpha 7 subunit antibody
    • Importin alpha S2 antibody
    • Importin subunit alpha 7 antibody
    • Importin subunit alpha-7 antibody
    • IPOA 7 antibody
    • IPOA7 antibody
    • Karyopherin alpha 6 antibody
    • Karyopherin alpha 6 (importin alpha 7) antibody
    • Karyopherin subunit alpha 6 antibody
    • Karyopherin subunit alpha-6 antibody
    • KPNA 6 antibody
    • KPNA 7 antibody
    • Kpna6 antibody
    • KPNA7 antibody
    • MGC17918 antibody
    • OTTHUMP00000004532 antibody
    see all

Anti-KPNA6 antibody images

  • Anti-KPNA6 antibody (ab82149) at 0.1 µg/ml + human skeletal muscle lysate in RIPA buffer at 35 µg
    Developed using the ECL technique

    Predicted band size : 60 kDa
    Observed band size : 60 kDa

    Exposure time : 1 hour

    Some minor background is detected and is blocked by the immunizing peptide.
  • ab82149 at 3.8 µg/ml staining KPNA6 in Human adrenal gland tissue by Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections). Steamed antigen retrieval with citrate buffer pH 6, AP-staining.

References for Anti-KPNA6 antibody (ab82149)

ab82149 has not yet been referenced specifically in any publications.

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